ArticleDigestive diseases and sciences1999
Intraesophageal pH monitoring during acid infusion in patients with systemic sclerosis.
Article in Digestive diseases and sciences, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Esophageal disease in progressive systemic sclerosis.Current treatment options in gastroenterology · 2008Article
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3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Incidental clinical observations suggest that buffering substances may accumulate in the distal esophagus of patients with systemic sclerosis. The aim of our study was to assess if the buffering capacity of the intraesophageal milieu is increased in patients with systemic sclerosis and if this effect can be correlated to some pathophysiological aspects of the disease. We recorded intraesophageal pH before and during a 10-min intraesophageal infusion of acid (HCl 0.01 N, 1 ml/min), as well as esophageal motility and clearance function, in 16 patients with systemic sclerosis and 10 healthy subjects. Esophageal buffering capacity expressed as the area under the curve of intraesophageal pH during acid infusion was significantly higher in the patients than in the controls, and this variable was directly correlated with esophageal clearing time. In conclusion, esophageal buffering capacity is increased in patients with systemic sclerosis and is possibly the consequence of the accumulation of buffering substances in the distal esophagus.
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