ArticleDigestive diseases and sciences1999
Effect of a dietary nonionic surfactant on small intestinal nutrient transport.
Article in Digestive diseases and sciences, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 6 citations in OpenAlex.
- Small bowel review: Normal physiology, part 1.Digestive diseases and sciences · 2003Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nonionic surfactants are commonly present in many prepared foods and drug formulations as stabilizing agents. The aim of the current study was to examine the effect of the common nonionic surfactant Tween-80 on jejunal glucose transport. New Zealand White rabbits (800-1200 g) were fasted for 24 hr. Jejunal tissue was stripped and mounted in short-circuited Ussing chambers. Unidirectional 3-O-methyl glucose fluxes were determined during a 15-min basal transport period and a subsequent 15-min experimental period after the mucosal addition of Tween-80 at final concentrations of 0.001%, 0.01%, 0.05%, and 0.1%. Tween-80 at final concentrations of 0.1% and 0.05% significantly increased net 3-O-methyl glucose transport over basal levels. The increase in Jnet was due to a significant increase in the absorptive Jm-s flux. Tween-80 at 0.01% and 0.001% did not significantly alter net glucose transport although Jm-s was significantly increased in the presence of 0.01% Tween-80. Tween-80, in concentrations commonly found in prepared foods, enhances the intestinal absorption of glucose.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.