ReviewLearning & memory (Cold Spring Harbor, N.Y.)
Interactions between depression and facilitation within neural networks: updating the dual-process theory of plasticity.
Review in Learning & memory (Cold Spring Harbor, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
18 citing papers in PubMed, 71 citations in OpenAlex.
- Article
- Electrophysiological Evidence for Impaired Central Pain Modulation in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- What a Sham(e): Sham-Controlled Conditioned Pain Modulation Effects on Pressure but Not Heat Pain Thresholds in Healthy Volunteers.European journal of pain (London, England) · 2025Article
- Habituation as optimal filtering.iScience · 2024Article
- Spinal stimulation for motor rehabilitation immediately modulates nociceptive transmission.Journal of neural engineering · 2022Article
- Tenderness of the Skin after Chemical Stimulation of Underlying Temporal and Thoracolumbar Fasciae Reveals Somatosensory Crosstalk between Superficial and Deep Tissues.Life (Basel, Switzerland) · 2021Article
- A Comparison Study of the Effect on IBS-D Rats among Ginger-Partitioned Moxibustion, Mild Moxibustion, and Laser Moxibustion.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- The capsaicin receptor TRPV1 is the first line defense protecting from acute non damaging heat: a translational approach.Journal of translational medicine · 2020Article
- The Effect of Moxibustion Stimulation on Local and Distal Skin Temperature in Healthy Subjects.Evidence-based complementary and alternative medicine : eCAM · 2019Article
- Altered Dynamics of the fMRI Response to Faces in Individuals with Autism.Journal of autism and developmental disorders · 2016Article
- Detection of central circuits implicated in the formation of novel pain memories.Journal of pain research · 2016Article
- Body awareness and pain habituation: the role of orientation towards somatic signals.Journal of behavioral medicine · 2015Article
- Aberrant face and gaze habituation in fragile x syndrome.The American journal of psychiatry · 2014Article
- Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer's disease model.Acta neuropathologica · 2014Article
- Neuronal competition for action potential initiation sites in a circuit controlling simple learning.Neuroscience · 2007Article
- Nonassociative learning as gated neural integrator and differentiator in stimulus-response pathways.Behavioral and brain functions : BBF · 2006Article
- Serotonin depletion does not prevent intrinsic sensitization in the leech.Learning & memory (Cold Spring Harbor, N.Y.)Article
- Sites of plasticity in the neural circuit mediating tentacle withdrawal in the snail Helix aspersa: implications for behavioral change and learning kinetics.Learning & memory (Cold Spring Harbor, N.Y.)Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Repetitive stimulation often results in habituation of the elicited response. However, if the stimulus is sufficiently strong, habituation may be preceded by transient sensitization or even replaced by enduring sensitization. In 1970, Groves and Thompson formulated the dual-process theory of plasticity to explain these characteristic behavioral changes on the basis of competition between decremental plasticity (depression) and incremental plasticity (facilitation) occurring within the neural network. Data from both vertebrate and invertebrate systems are reviewed and indicate that the effects of depression and facilitation are not exclusively additive but, rather, that those processes interact in a complex manner. Serial ordering of induction of learning, in which a depressing locus precedes the modulatory system responsible for inducing facilitation, causes the facilitation to wane. The parallel and/or serial expression of depression and waning facilitation within the stimulus-response pathway culminates in the behavioral changes that characterize dual-process learning. A mathematical model is presented to formally express and extend understanding of the interactions between depression and facilitation.
Indexed as
Identifiers
10489261PMC311261W1941323872What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.