ArticleJournal of clinical microbiology1999
The cps genes of Streptococcus suis serotypes 1, 2, and 9: development of rapid serotype-specific PCR assays.
Article in Journal of clinical microbiology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 93 citations in OpenAlex.
- Immunization with Streptococcus suis bacterin plus recombinant Sao protein in sows conveys passive immunity to their piglets.BMC veterinary research · 2017Trial
- Antimicrobial Resistance, Serotypes, Virulence Gene Profiles, and Molecular Characterization ofAntibiotics (Basel, Switzerland) · 2026Article
- Epidemiological investigation and pathogenicity ofFrontiers in microbiology · 2025Article
- Article
- Genomic epidemiology inHeliyon · 2024Review
- Development and application of a quadruplex TaqMan fluorescence quantitative PCR typing method forFrontiers in cellular and infection microbiology · 2024Article
- Preparation of Aditoprim Injection againstPharmaceutics · 2022Article
- Accelerated loop-mediated isothermal amplification method for the rapid detection of Streptococcus suis serotypes 2 and 14 based on single nucleotide polymorphisms.Frontiers in cellular and infection microbiology · 2022Article
- Article
- Clonal expansion of a virulent Streptococcus suis serotype 9 lineage distinguishable from carriage subpopulations.Scientific reports · 2019Article
- Review
- Exploring target-specific primer extension in combination with a bead-based suspension array for multiplexed detection and typing using Streptococcus suis as a model pathogen.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2018Article
- Serotypes of Streptococcus suis isolated from healthy pigs in Phayao Province, Thailand.BMC research notes · 2017Article
- Determining Streptococcus suis serotype from short-read whole-genome sequencing data.BMC microbiology · 2016Article
- Simultaneous Quantification and Differentiation of Streptococcus suis Serotypes 2 and 9 by Quantitative Real-Time PCR, Evaluated in Tonsillar and Nasal Samples of Pigs.Pathogens (Basel, Switzerland) · 2016Article
- Current Taxonomical Situation of Streptococcus suis.Pathogens (Basel, Switzerland) · 2016Review
- Impact of Sub-Inhibitory Concentrations of Amoxicillin on Streptococcus suis Capsule Gene Expression and Inflammatory Potential.Pathogens (Basel, Switzerland) · 2016Article
- Exposure of feral swine (Sus scrofa) in the United States to selected pathogens.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2015Article
- Assessing the Metabolic Diversity of Streptococcus from a Protein Domain Point of View.PloS one · 2015Article
- Characterization of multi-drug tolerant persister cells in Streptococcus suis.BMC microbiology · 2014Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We developed three type-specific PCR assays for the rapid and sensitive detection of Streptococcus suis serotype 1 (plus 14), serotype 2 (plus 1/2), and serotype 9 strains in tonsillar specimens from pigs. The PCR primers were based on the sequences of type-specific capsular genes of S. suis serotype 1, 2, and 9 strains. We recently characterized a major part of the capsular biosynthesis (cps) locus of S. suis serotype 2. Here we extended these studies and characterized major parts of the cps loci of S. suis serotypes 1 and 9. Type-specific genes were identified by cross-hybridization experiments between the individual cps genes and chromosomal DNAs from the 35 different serotypes. Four genes of S. suis serotype 1 specifically hybridized with serotype 1 and 14 strains only. Five genes of S. suis serotype 2 specifically hybridized with serotype 2 and 1/2 strains only, and two genes of S. suis serotype 9 specifically hybridized with serotype 9 strains. Until now rapid and sensitive diagnostic tests were available only for pathogenic strains of serotype 2 and highly pathogenic strains of serotype 1. The serotype-specific PCR assays can therefore be useful tools for the identification of serotype 1, 14, 2, 1/2, and 9 strains both for diagnostic purposes and in epidemiological and transmission studies. Therefore, these tests may facilitate control and eradication programs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.