ArticleJournal of clinical microbiology1999
Follow-up of Staphylococcus aureus nasal carriage after 8 years: redefining the persistent carrier state.
Article in Journal of clinical microbiology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04104178 (A Randomized Placebo-controlled Double-blinded Trial of the Treatment of MRSA Throat Carriage With Either Standard Decolonization Therapy or Standard Decolonization Therapy Combined With Oral Clindamycin), which is not on this map. Cited by 63 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Placebo-controlled Double-blinded Trial of the Treatment of MRSA Throat Carriage With Either Standard Decolonization Therapy or Standard Decolonization Therapy Combined With Oral Clindamycin
Who cites it
63 citing papers in PubMed.
- Trial
- Molecular epidemiology of Staphylococcus aureus colonization in 2 long-term care facilities.Infection control and hospital epidemiology · 2006Trial
- Fusidic acid cream in the treatment of impetigo in general practice: double blind randomised placebo controlled trial.BMJ (Clinical research ed.) · 2002Trial
- Staphylococci in high resolution: Capturing diversity within the human nasal microbiota.Cell reports · 2025Article
- Nasal Staphylococcus aureus Carriage and Antimicrobial Resistance Profiles Among Community-Dwelling Adults in Jiangsu, China.Infectious diseases and therapy · 2024Article
- Stigmas and Petals ofTheScientificWorldJournal · 2024Article
- A Quantitative Assessment of Staphylococcus aureus Community Carriage in Yuma, Arizona.The Journal of infectious diseases · 2023Article
- Are Staphylococcus aureus Carrier Types Evidence of Population Heterogeneity?American journal of epidemiology · 2023Article
- Worsening Glycemia Increases the Odds of Intermittent but Not Persistent Staphylococcus aureus Nasal Carriage in Two Cohorts of Mexican American Adults.Microbiology spectrum · 2022Article
- Everybody nose: molecular and clinical characteristics of nasal colonization during active methicillin-resistant Staphylococcus aureus bloodstream infection.BMC infectious diseases · 2022Article
- Transcriptional adaptation of staphylococci during colonization of the authentic human environment: An overview of transcriptomic changes and their relationship to physiological conditions.Frontiers in cellular and infection microbiology · 2022Review
- Survival of Staphylococcus aureus on sampling swabs stored at different temperatures.Journal of applied microbiology · 2021Article
- Staphylococcus aureus Panton-Valentine Leukocidin triggers an alternative NETosis process targeting mitochondria.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021Article
- Long-Term Sinonasal Carriage ofMicroorganisms · 2021Article
- Methicillin-ResistantInfection and drug resistance · 2020Review
- Patterns and Predictors ofJournal of clinical microbiology · 2019Article
- Pre-operative Decolonization as a Strategy to Reduce Surgical Site Infection.Current infectious disease reports · 2019Review
- Longitudinal Population Dynamics ofFrontiers in genetics · 2019Article
- Face Mask Use and Persistence of Livestock-associatedEnvironmental health perspectives · 2018Article
- Drivers for Livestock-Associated Methicillin-Resistant Staphylococcus Aureus Spread Among Danish Pig Herds - A Simulation Study.Scientific reports · 2018Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies of Staphylococcus aureus nasal carriage have distinguished three carriage patterns: persistent, intermittent, and noncarriage. The criteria used to identify these carriage patterns have been inconsistent. In 1988 the S. aureus nasal carrier index, i.e., the proportion of nasal swab specimen cultures yielding S. aureus, was determined for 91 staff members of various departments of a large university hospital by obtaining weekly nasal swab specimens for culture over a 12-week period. Thirty-three (36%) persons had carrier indices of 0.80 or higher, 15 (17%) had indices between 0.1 and 0.7, and 43 (47%) had indices of zero. In 1995, 17 individuals with carrier indices of 0.80 or higher in 1988 were available for reexamination. For 12 (71%) of these individuals, S. aureus was again isolated from a single nasal swab, i.e., from each individual with a 1988 carrier index of 1.0 but from only half of those with indices below 1.0. Genotyping (by randomly amplified polymorphic DNA analysis and pulsed-field gel electrophoresis) of all S. aureus strains showed that strains isolated from only three individuals, all with 1988 carrier indices of 1.0, in 1988 and 1995 showed genetic similarity. In conclusion, persistent S. aureus nasal carriage is a unique characteristic of a fraction of the population, and the attribute "persistent" should be confined to those individuals for whom serial nasal swab specimen cultures consistently yield S. aureus.
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