ArticleBritish journal of cancer1999
Quantifying the effect of population mixing on childhood leukaemia risk: the Seascale cluster.
Article in British journal of cancer, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed.
- A Historical Survey of Key Epidemiological Studies of Ionizing Radiation Exposure.Radiation research · 2024Review
- The Association Between Childhood Leukemia and Population Mixing: An Artifact of Focusing on Clusters?Epidemiology (Cambridge, Mass.) · 2019Article
- Childhood cancer research in oxford III: The work of CCRG on ionising radiation.British journal of cancer · 2018Article
- A case-control study of occupational contact levels in the childhood leukaemia cluster at Seascale, Cumbria, UK.BMJ open · 2015Article
- Race/ethnicity and the risk of childhood leukaemia: a case-control study in California.Journal of epidemiology and community health · 2015Article
- Updated investigations of cancer excesses in individuals born or resident in the vicinity of Sellafield and Dounreay.British journal of cancer · 2014Article
- Epidemiological evidence of childhood leukaemia around nuclear power plants.Dose-response : a publication of International Hormesis Society · 2014Article
- Perspectives on the causes of childhood leukemia.Chemico-biological interactions · 2012Review
- Unusual space-time patterning of the Fallon, Nevada leukemia cluster: Evidence of an infectious etiology.Chemico-biological interactions · 2012Article
- Childhood leukaemia, nuclear sites, and population mixing.British journal of cancer · 2011Review
- Population mixing, socioeconomic status and incidence of childhood acute lymphoblastic leukaemia in England and Wales: analysis by census ward.British journal of cancer · 2008Article
- Childhood leukaemia and population movements in France, 1990-2003.British journal of cancer · 2008Article
- Residential mobility and risk of childhood acute lymphoblastic leukaemia: an ecological study.British journal of cancer · 2007Article
- Childhood leukaemia and ordnance factories in west Cumbria during the Second World War.British journal of cancer · 2006Article
- Urbanisation and incidence of acute lymphocytic leukaemia among United States children aged 0-4.British journal of cancer · 2005Article
- Incidence of childhood leukaemia in the vicinity of nuclear sites in France, 1990-1998.British journal of cancer · 2004Article
- Review
- Childhood leukaemia incidence and the population mixing hypothesis in US SEER data.British journal of cancer · 2004Article
- Probability estimates for the unique childhood leukemia cluster in Fallon, Nevada, and risks near other U.S. Military aviation facilities.Environmental health perspectives · 2004Article
- Cancer in the offspring of radiation workers: an investigation of employment timing and a reanalysis using updated dose information.British journal of cancer · 2003Article
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2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
A statistical model was developed based on Poisson regression of incidence of childhood leukaemia and non-Hodgkin's lymphoma (NHL) in relation to population mixing among all 119 539 children born 1969-1989 to mothers living in Cumbria, north-west England, (excluding Seascale). This model was used to predict the number of cases in Seascale (the village adjacent to the Sellafield nuclear installation) children, born 1950-1989 and diagnosed before 1993. After allowing for age, the incidence of acute lymphoblastic leukaemia (ALL) and NHL was significantly higher among children born in areas with the highest levels of population mixing, relative risk (RR) = 11.7 (95% confidence interval (CI) 3.2-43) and was highest among children of incomers. The model predicted up to 3.0 (95% CI 1.3-6.0) cases of ALL/NHL in children born in Seascale compared to six observed and 2.0 (95% CI 1.0-3.4) cases in children resident, but not born, in Seascale compared to two observed. Population mixing is a significant risk factor for ALL/NHL, especially in young children, accounting for over 50% of cases in Cumbria and most cases in Seascale.
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