ArticleJournal of neurology, neurosurgery, and psychiatry1999
Night time versus daytime transient ischaemic attack and ischaemic stroke: a prospective study of 110 patients.
Article in Journal of neurology, neurosurgery, and psychiatry, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Intravenous thrombolytic treatment and endovascular thrombectomy for ischaemic wake-up stroke.The Cochrane database of systematic reviews · 2021Pooled it
- Recanalisation therapies for wake-up stroke.The Cochrane database of systematic reviews · 2018Pooled it
- Relationship between stroke onset timing and clinical outcomes in ischemic and hemorrhagic strokes: a systematic review.International journal of cardiology. Cardiovascular risk and prevention · 2026Review
- Neuroendocrine Stress Response in Acute Stroke: Physiological and Clinical Perspectives.Cureus · 2026Review
- The time dimension to stroke: Circadian effects on stroke outcomes and mechanisms.Neurochemistry international · 2023Article
- Tenecteplase in wake-up ischemic stroke trial: Protocol for a randomized-controlled trial.International journal of stroke : official journal of the International Stroke Society · 2021Article
- Wake-up strokes are linked to obstructive sleep apnea and worse early functional outcome.Brain and behavior · 2021Observational
- European Stroke Organisation (ESO) guidelines on intravenous thrombolysis for acute ischaemic stroke.European stroke journal · 2021Article
- Emergency department patient experience: Same location, same provider, different scores by different survey methods.World journal of emergency medicine · 2019Article
- Increased Risk of Ischemic Stroke during Sleep in Apneic Patients.Journal of clinical neurology (Seoul, Korea) · 2018Article
- Sleep and clocks - implications for brain health.Neurobiology of sleep and circadian rhythms · 2017Article
- Daily Variation in the Occurrence of Different Subtypes of Stroke.Stroke research and treatment · 2017Article
- Changes in chronotype after stroke: a pilot study.Frontiers in neurology · 2014Article
- Early sleep apnea screening on a stroke unit is feasible in patients with acute cerebral ischemia.Journal of neurology · 2013Article
- Prevalence of sleep-disordered breathing in acute ischemic stroke as determined using a portable sleep apnea monitoring device in Korean subjects.Sleep & breathing = Schlaf & Atmung · 2011Article
- Article
- Autoregulation of the cerebral circulation during sleep in newborn lambs.The Journal of physiology · 2005Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIschaemic stroke occurs only in 20%-40% of patients at night. The aim of the study was to compare sleep and stroke characteristics of patients with and without night time onset of acute ischaemic cerebrovascular events.
methodsA consecutive series of 110 patients with transient ischaemic attack (n=45) or acute ischaemic stroke (n=65) was studied prospectively by means of a standard protocol which included assessment of time of onset of symptoms, sleep, and stroke characteristics. An overnight polysomnography was performed after the onset of transient ischaemic attack/stroke in 71 patients. Stroke and sleep characteristics of patients with and without cerebrovascular events occurring at night (between midnight and 0600) were compared.
resultsA night time onset of transient ischaemic attack or stroke was reported by 23 (21%) of 110 patients. Patients with daytime and night time events were similar in demographics; risk factors; associated vascular diseases; clinical and polysomnographic sleep characteristics (including severity of sleep apnoea); and stroke severity, aetiology, and outcome. Only the diastolic blood pressure at admission was significantly lower in patients with night time events (74 v 82 mm Hg, p=0.01).
conclusionsPatients with night time and daytime transient ischaemic attack/stroke are similar in sleep and stroke characteristics. Diastolic hypotension may predispose to night time cerebrovascular events. Factors not assessed in this study probably account for the circadian variation in the frequency of transient ischaemic attack and acute ischaemic stroke.
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