ArticleGut1999
Intestinal transplantation in children with chronic intestinal pseudo-obstruction.
Article in Gut, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.
- A meta-analysis of clinical outcome of intestinal transplantation in patients with total intestinal aganglionosis.Pediatric surgery international · 2017Pooled it
- A meta-analysis of clinical outcome in patients with total intestinal aganglionosis.Pediatric surgery international · 2009Pooled it
- Incidence, diagnostics, therapeutic management and outcomes of paediatric intestinal pseudo-obstruction in the Netherlands: A 20-year retrospective cohort study.Journal of pediatric gastroenterology and nutrition · 2025Observational
- Gastroesophageal Reflux Disease and Foregut Dysmotility in Children with Intestinal Failure.Nutrients · 2020Review
- Pediatric Intestinal Pseudo-obstruction in the Era of Genetic Sequencing.Current gastroenterology reports · 2019Review
- High-resolution colonic manometry and its clinical application in patients with colonic dysmotility: A review.World journal of clinical cases · 2019Review
- Assessment and outcome of pediatric intestinal pseudo-obstruction: A tertiary-care-center experience from Turkey.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2019Article
- An ANMS-NASPGHAN consensus document on esophageal and antroduodenal manometry in children.Neurogastroenterology and motility · 2018Review
- Pre-emptive Intestinal Transplant: The Surgeon's Point of View.Digestive diseases and sciences · 2017Review
- Choice of Allograft in Patients Requiring Intestinal Transplantation: A Critical Review.Canadian journal of gastroenterology & hepatology · 2017Review
- Nationwide survey on adult type chronic intestinal pseudo-obstruction in surgical institutions in Japan.Surgery today · 2012Article
- Chronic idiopathic intestinal pseudo-obstruction treated by near total small bowel resection: a 20-year experience.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2010Article
- Outcomes in children after intestinal transplant.Pediatrics · 2010Article
- Short bowel syndrome: parenteral nutrition versus intestinal transplantation. Where are we today?Digestive diseases and sciences · 2007Review
- Acute on chronic intestinal pseudo-obstruction as a cause of death in a previously healthy twenty-year-old male.Digestive diseases and sciences · 2006Article
- Primary intestinal autoimmune disease as a cause of chronic intestinal pseudo-obstruction.Gut · 2005Article
- Intestinal transplantation.Indian journal of pediatrics · 2003Review
- Small bowel review: Normal physiology, part 2.Digestive diseases and sciences · 2003Review
- Long-term outcome of congenital intestinal pseudoobstruction.Digestive diseases and sciences · 2002Article
- Chronic vomiting in children: new insights into diagnosis.Current gastroenterology reports · 2001Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChildren with chronic intestinal pseudo-obstruction (CIPO) often require total parenteral nutrition (TPN) which puts them at risk of liver failure and recurrent line infections. Intestinal transplantation has become a therapeutic option for TPN dependent children with intestinal failure who are failing management with TPN.
aimsTo investigate the outcome of children with CIPO referred for intestinal transplantation.
methodsA retrospective review was carried out of records and diagnostic studies from 27 patients with CIPO referred for intestinal transplantation.
resultsFive children were not listed for transplantation: two because of parental decision, two because of suspicion of Munchausen syndrome by proxy, and one because he tolerated enteral nutrition. Six are still TPN dependent and awaiting transplantation. Eight children died awaiting transplantation. Eight children underwent transplantation. Three died (two months, seven months, and four years after transplant). Five children are alive with a median follow up of 2.6 years (range two months to six years). All transplanted children were able to tolerate full enteral feedings. The postoperative course was complicated by dumping syndrome, Munchausen syndrome by proxy, narcotic withdrawal, and uncovering of achalasia. Conclusion-Intestinal transplantation may be a life saving procedure in children with CIPO. Early referral and thorough pretransplant evaluation are keys to successful transplantation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.