ArticleGut1999
Mesenteric blood flow is related to disease activity and risk of relapse in ulcerative colitis: a prospective follow up study.
Article in Gut, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Doppler ultrasound, a noninvasive tool for the study of mesenteric arterial flow in systemic sclerosis: a cross-sectional study of a patient cohort with review and meta-analysis of the literature.Internal and emergency medicine · 2025Pooled it
- [Imaging in chronic inflammatory bowel disease].Innere Medizin (Heidelberg, Germany) · 2025Review
- Portal congestion and intestinal edema in hospitalized patients with heart failure.Heart and vessels · 2018Observational
- How to perform gastrointestinal ultrasound: Anatomy and normal findings.World journal of gastroenterology · 2017Review
- The use of ultrasound in inflammatory bowel disease.Annals of gastroenterology · 2017Review
- Inflammatory bowel disease-the role of cross-sectional imaging techniques in the investigation of the small bowel.Insights into imaging · 2015Article
- Crohn's disease activity assessed by Doppler sonography: the role of aortic flow parameters.Clinics (Sao Paulo, Brazil) · 2013Article
- Huang Qi Jian Zhong Pellet Attenuates TNBS-Induced Colitis in Rats via Mechanisms Involving Improvement of Energy Metabolism.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- Evaluation of inflammatory activity in Crohn's disease and ulcerative colitis.World journal of gastroenterology · 2012Review
- Ultrasonographic evaluation of bowel wall thickness and intramural blood flow in ulcerative colitis.ISRN gastroenterology · 2012Article
- Diagnostics in inflammatory bowel disease: ultrasound.World journal of gastroenterology · 2011Review
- Article
- Sonographic evaluation of inflammatory bowel disease: a prospective, blinded, comparative study.Pediatric radiology · 2006Article
- Type I intestinal lymphangiectasia treated successfully with slow-release octreotide.Digestive diseases and sciences · 2003Article
- Diagnostic methodologies: serology, endoscopy, and radiology.Current gastroenterology reports · 2001Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe diagnostic significance of increased splanchnic blood flow in ulcerative colitis is unclear. This prospective study was therefore undertaken to define the role of Doppler sonography in the assessment of disease activity and in the prediction of early relapse. SUBJECTS/
methodsSplanchnic flowmetry was performed in 76 patients with ulcerative colitis (47 with active disease and 29 in remission), six with infectious colitis, and 13 healthy controls during fasting and 30 minutes after ingestion of a standardised meal. Twenty seven of the patients with ulcerative colitis and all patients with infectious colitis were investigated during the active state as well as in clinical remission and followed up for six months. Flow velocity and pulsatility index (PI) of the superior (SMA) and inferior (IMA) mesenteric arteries and the portal vein were related to clinical (Truelove index), laboratory (C-reactive protein), and endoscopic (Sutherland index) parameters of disease activity.
resultsThe mean flow velocity of the IMA correlated closest with clinical activity (Truelove, r = 0.41, p<0.005), the PI with C-reactive protein (r = 0.30, p<0.05), and endoscopic activity (r = 0.45, p<0.001). All patients in remission after six months (14/14) or with infectious colitis (6/6) showed an increase in PI of the IMA compared with the initial measurement during active disease (mean increase for ulcerative colitis +36% and for infectious colitis +77%). In contrast, most patients with later relapse or surgery (11/13) had decreased PI during initial remission (mean decrease -12%). The positive predictive value of this index for maintenance of remission was 0.77. Flow variables of the SMA and portal vein displayed weaker correlations.
conclusionsFlow measurements in the IMA are closely related to clinical and endoscopic disease activity in patients with ulcerative colitis. Repeated measurement of the PI allows estimation of the risk of recurrence.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.