ArticleAmerican journal of human genetics1999
A generalization of the transmission/disequilibrium test for uncertain-haplotype transmission.
Article in American journal of human genetics, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 200 papers, 1 of them a synthesis that pooled it.
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Who cites it
200 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis in psychiatric genetics.Current psychiatry reports · 2005Pooled it
- Association of the calcyon gene (DRD1IP) with attention deficit/hyperactivity disorder.Molecular psychiatry · 2005Trial
- A haplotype within the DISC1 gene is associated with visual memory functions in families with a high density of schizophrenia.Molecular psychiatry · 2005Trial
- Separate and interacting effects within the catechol-O-methyltransferase (COMT) are associated with schizophrenia.Molecular psychiatry · 2005Trial
- Support for EKN1 as the susceptibility locus for dyslexia on 15q21.Molecular psychiatry · 2004Trial
- Replication of 1q42 linkage in Finnish schizophrenia pedigrees.Molecular psychiatry · 2004Trial
- Case-Parent Trio Studies in Cleft Lip and Palate.Global medical genetics · 2020Review
- A mouse-to-man candidate gene study identifies association of chronic otitis media with the loci TGIF1 and FBXO11.Scientific reports · 2017Article
- Family-Based Multi-SNP X Chromosome Analysis Using Parent Information.Frontiers in genetics · 2016Article
- Quantitative trait locus analysis of parasite density reveals that HbS gene carriage protects severe malaria patients against Plasmodium falciparum hyperparasitaemia.Malaria journal · 2015Article
- A haplotype-based framework for group-wise transmission/disequilibrium tests for rare variant association analysis.Bioinformatics (Oxford, England) · 2015Article
- Association of the KCNJ5 gene with Tourette Syndrome and Attention-Deficit/Hyperactivity Disorder.Genes, brain, and behavior · 2014Article
- Imputation without doing imputation: a new method for the detection of non-genotyped causal variants.Genetic epidemiology · 2014Article
- Mega2: validated data-reformatting for linkage and association analyses.Source code for biology and medicine · 2014Article
- Incorporating parental information into family-based association tests.Biostatistics (Oxford, England) · 2013Article
- The association between DRD2/ANKK1 and genetically informed measures of alcohol use and problems.Addiction biology · 2013Article
- Association between the 2-bp deletion polymorphism in the duplicated version of the alpha7 nicotinic receptor gene and P50 sensory gating.European journal of human genetics : EJHG · 2013Article
- Increasing the power of association studies with affected families, unrelated cases and controls.Frontiers in genetics · 2013Article
- Dosage transmission disequilibrium test (dTDT) for linkage and association detection.PloS one · 2013Article
- Detection and impact of rare regulatory variants in human disease.Frontiers in genetics · 2013Article
140 more citing papers are in PubMed but not listed here.
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1 author.
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No grant is acknowledged in the PubMed record.
Abstract
A new transmission/disequilibrium-test statistic is proposed for situations in which transmission is uncertain. Such situations arise when transmission of a multilocus marker haplotype is considered, since haplotype phase is often unknown in a substantial number of instances. Even for single-locus markers, transmission is uncertain if one or both parents are missing. In both these situations, uncertainty may be reduced by the typing of further siblings, whose disease status may be unaffected or unknown. The proposed test is a score test based on a partial score function that omits the terms most influenced by hidden population stratification.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.