ArticleJournal of virology1999
Discovery of a new endogenous type C retrovirus (FcEV) in cats: evidence for RD-114 being an FcEV(Gag-Pol)/baboon endogenous virus BaEV(Env) recombinant.
Article in Journal of virology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 70 citations in OpenAlex.
- Gammaretrovirus Infections in Humans in the Past, Present, and Future: Have We Defeated the Pathogen?Pathogens (Basel, Switzerland) · 2026Review
- Epigenetic motifs distinguishing endogenous from exogenous retroviral integrants.Journal of virology · 2025Article
- FeLIX is a restriction factor for mammalian retrovirus infection.Journal of virology · 2024Article
- Multiple recombination events between endogenous retroviral elements and feline leukemia virus.Journal of virology · 2024Article
- Envelope Recombination: A Major Driver in Shaping Retroviral Diversification and Evolution within the Host Genome.Viruses · 2023Review
- Cross-species transmission of an ancient endogenous retrovirus and convergent co-option of its envelope gene in two mammalian orders.PLoS genetics · 2022Article
- Convergent evolution of antiviral machinery derived from endogenous retrovirus truncated envelope genes in multiple species.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- A novel class III endogenous retrovirus with a class I envelope gene in African frogs with an intact genome and developmentally regulated transcripts in Xenopus tropicalis.Retrovirology · 2021Article
- The origin of porcine endogenous retroviruses (PERVs).Archives of virology · 2021Review
- Tracking the Fate of Endogenous Retrovirus Segregation in Wild and Domestic Cats.Journal of virology · 2019Article
- Tracking the Continuous Evolutionary Processes of an Endogenous Retrovirus of the Domestic Cat: ERV-DC.Viruses · 2018Review
- Transmission, Evolution, and Endogenization: Lessons Learned from Recent Retroviral Invasions.Microbiology and molecular biology reviews : MMBR · 2018Review
- Existence of Two Distinct Infectious Endogenous Retroviruses in Domestic Cats and Their Different Strategies for Adaptation to Transcriptional Regulation.Journal of virology · 2016Article
- A novel endogenous betaretrovirus in the common vampire bat (Desmodus rotundus) suggests multiple independent infection and cross-species transmission events.Journal of virology · 2015Article
- Multiple invasions of an infectious retrovirus in cat genomes.Scientific reports · 2015Article
- Cross-Species Transmission and Differential Fate of an Endogenous Retrovirus in Three Mammal Lineages.PLoS pathogens · 2015Article
- Contamination of live attenuated vaccines with an infectious feline endogenous retrovirus (RD-114 virus).Archives of virology · 2014Review
- Pushing the endogenous envelope.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2013Review
- The extraordinary evolutionary history of the reticuloendotheliosis viruses.PLoS biology · 2013Article
- Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Analysis of a cat genomic DNA library showed that cats harbor a previously unrecognized endogenous type C retrovirus, whose env gene has homology to the murine Fv-4 resistance gene. This unique retrovirus, designated FcEV (Felis catus endogenous retrovirus), has a type C pol gene, closely related to the primate Papio cynocephalus endogenous virus (PcEV) pol, not overlapping the env gene, unlike in other type C retroviruses, and is presumably present in a higher copy number than RD-114. Phylogenetic analysis of FcEV and RD-114 fragments amplified from cat species and comparison with baboon endogenous virus (BaEV) fragments from monkeys suggested that RD-114 does not represent the cat strain of BaEV but is actually a new recombinant between FcEV type C genes and the env gene of BaEV. Although BaEV did appear to have infected an ancestor of the domestic cat lineage, it was a de novo recombinant that made its way into the cat germ line.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.