Evidence map›Paper›PMID 10478801›Full record

ArticleIn vitro cellular & developmental biology. Animal1999

Nitric oxide donors, sodium nitroprusside and S-nitroso-N-acetylpencillamine, stimulate myoblast proliferation in vitro.

J A Ulibarri, P E Mozdziak, E Schultz, C Cook, T M Best

Abstract read
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In one paragraph

Article in In vitro cellular & developmental biology. Animal, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Redox Control of Skeletal Muscle Regeneration.Antioxidants & redox signaling · 2017
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Nitric oxide and cancer.World journal of hepatology · 2010
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

J A UlibarriDepartment of Pathology, University of Wisconsin Medical School, Madison 53711, USA.
P E Mozdziak
E Schultz
C Cook
T M Best

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nitric oxide (NO) is an inter- and intracellular messenger involved in a variety of physiologic and pathophysiologic conditions. The effect of two NO donors, sodium nitroprusside (SNP) and S-nitroso-N-acetylpenicillamine (SNAP) and their effect on myoblast proliferation was examined. Both donors stimulated an increase in myoblast cell number over a range (1-10 microM) of donor concentrations. However, 50 microM SNAP inhibited myoblast proliferation. Cell numbers from cultures treated with degraded 10 microM SNAP were equivalent to the control. Therefore, it appears NO can stimulate as well as inhibit myoblast proliferation.

Indexed as

AnimalsCell DivisionCells, CulturedMuscle, SkeletalNitric OxideNitric Oxide DonorsNitroprussidePenicillamineS-Nitroso-N-AcetylpenicillamineTurkeysNitric OxideNitric Oxide DonorsNitroprussidePenicillamineS-Nitroso-N-AcetylpenicillamineNASA Discipline MusculoskeletalNon-NASA Center

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.