Evidence map›Paper›PMID 10475569›Full record

ArticleThe Histochemical journal1999

NADPH-diaphorase and NOS-1 positive ganglion cells are found in the rat vallate papilla/von Ebner gland complex.

A Sbarbati, C Crescimanno, V De Rossi, P Bernardi, F Osculati

Abstract read
PubMed Publisher
In one paragraph

Article in The Histochemical journal, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

A SbarbatiInstitute of Human Anatomy and Histology, University of Verona, Italy.
C Crescimanno
V De Rossi
P Bernardi
F Osculati
University of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nervous system of the vallata papilla and von Ebner glands was investigated in the rat tongue. Cells involved in the production of nitric oxide were identified by immunohistochemical detection of neuronal nitric oxide synthase type-1 and by cytochemical detection of NADPH-diaphorase. The analysis of serial sections showed that a ganglion composed of about 180-190 neuronal cells was present between the vallata papilla and von Ebner glands. These cells were positive for nitric oxide synthase type-1 and NADPH-diaphorase. From the ganglion, we observed nitrergic fibres running: (a) in the lamina propria of the receptor-free mucosa; (b) just below the gustatory epithelium; (c) in the von Ebner glands; and (d) around the vascular system of the vallata papilla. Our study suggests that the nitrergic ganglion cells may mediate interactions between chemoreceptorial systems in the vallata papilla and secretory cells in the von Ebner glands and that nitric oxide could be involved in the regulation of the blood supply to the vallata papilla and in the regulation of the von Ebner glands.

Indexed as

AnimalsFemaleGanglia, SensoryImmunohistochemistryMaleMicroscopyNADPH DehydrogenaseNerve FibersNitric Oxide SynthaseNitric Oxide Synthase Type IRatsRats, WistarTongueNADPH DehydrogenaseNitric Oxide SynthaseNitric Oxide Synthase Type INos1 protein, rat

Identifiers

PMID10475569
OpenAlexW135323495

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.