ArticleGenetics1999
Arabidopsis PAI gene arrangements, cytosine methylation and expression.
Article in Genetics, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed, 106 citations in OpenAlex.
- Genome-wide CG hypomethylation of theProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Gene body methylation regulates gene expression and mediates phenotypic diversity in natural Arabidopsis populations.Nature plants · 2025Article
- Population epigenetics: DNA methylation in the plant omics era.Plant physiology · 2024Article
- Epiallelic variation of non-coding RNA genes and their phenotypic consequences.Nature communications · 2024Article
- Extensive sequence duplication in Arabidopsis revealed by pseudo-heterozygosity.Genome biology · 2023Article
- Triggers and mediators of epigenetic remodeling in plants.Frontiers in epigenetics and epigenomics · 2023Review
- Nucleotide mismatches prevent intrinsic self-silencing of hpRNA transgenes to enhance RNAi stability in plants.Nature communications · 2022Article
- Decoding the sorghum methylome: understanding epigenetic contributions to agronomic traits.Biochemical Society transactions · 2022Article
- Assessment of natural DNA methylation variation and its association with economically important traits in dolichos bean (Lablab purpureus L. Var. Lignosus) using AMP-PCR assay.Journal of applied genetics · 2021Article
- Peptone-Induced Physio-Biochemical Modulations Reduce Cadmium Toxicity and Accumulation in Spinach (Plants (Basel, Switzerland) · 2020Article
- A genome assembly and the somatic genetic and epigenetic mutation rate in a wild long-lived perennial Populus trichocarpa.Genome biology · 2020Article
- Inter-individual variation in DNA methylation is largely restricted to tissue-specific differentially methylated regions in maize.BMC plant biology · 2017Article
- Putting DNA methylation in context: from genomes to gene expression in plants.Biochimica et biophysica acta. Gene regulatory mechanisms · 2017Review
- The expanding world of small RNAs in plants.Nature reviews. Molecular cell biology · 2015Review
- Century-scale methylome stability in a recently diverged Arabidopsis thaliana lineage.PLoS genetics · 2015Article
- Inheritance patterns and stability of DNA methylation variation in maize near-isogenic lines.Genetics · 2014Article
- Covering your bases: inheritance of DNA methylation in plant genomes.Molecular plant · 2014Article
- Roles, and establishment, maintenance and erasing of the epigenetic cytosine methylation marks in plants.Journal of genetics · 2013Review
- Epigenetic and genetic influences on DNA methylation variation in maize populations.The Plant cell · 2013Article
- Epialleles in plant evolution.Genome biology · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Previous analysis of the PAI tryptophan biosynthetic gene family in Arabidopsis thaliana revealed that the Wassilewskija (WS) ecotype has four PAI genes at three unlinked sites: a tail-to-tail inverted repeat at one locus (PAI1-PAI4) plus singlet genes at two other loci (PAI2 and PAI3). The four WS PAI genes are densely cytosine methylated over their regions of DNA identity. In contrast, the Columbia (Col) ecotype has three singlet PAI genes at the analogous loci (PAI1, PAI2, and PAI3) and no cytosine methylation. To understand the mechanism of PAI gene duplication at the polymorphic PAI1 locus, and to investigate the relationship between PAI gene arrangement and PAI gene methylation, we analyzed 39 additional ecotypes of Arabidopsis. Six ecotypes had PAI arrangements similar to WS, with an inverted repeat and dense PAI methylation. All other ecotypes had PAI arrangements similar to Col, with no PAI methylation. The novel PAI-methylated ecotypes provide insights into the mechanisms underlying PAI gene duplication and methylation, as well as the relationship between methylation and gene expression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.