ArticleGenetics1999
Switch in codon bias and increased rates of amino acid substitution in the Drosophila saltans species group.
Article in Genetics, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 50 citations in OpenAlex.
- Phylogeny of Drosophila saltans group (Diptera: Drosophilidae) based on morphological and molecular evidence.PloS one · 2022Article
- Review
- Population genomic analysis of base composition evolution in Drosophila melanogaster.Genome biology and evolution · 2012Article
- Strong evidence for lineage and sequence specificity of substitution rates and patterns in Drosophila.Molecular biology and evolution · 2009Article
- Locus-specific decoupling of base composition evolution at synonymous sites and introns along the Drosophila melanogaster and Drosophila sechellia lineages.Genome biology and evolution · 2009Article
- Is the evolutionary history of the O-type P element in the saltans and willistoni groups of Drosophila similar to that of the canonical P element?Journal of molecular evolution · 2007Article
- Article
- Article
- Minor shift in background substitutional patterns in the Drosophila saltans and willistoni lineages is insufficient to explain GC content of coding sequences.BMC biology · 2006Article
- Strong regional heterogeneity in base composition evolution on the Drosophila X chromosome.Genetics · 2006Article
- Convergent neofunctionalization by positive Darwinian selection after ancient recurrent duplications of the xanthine dehydrogenase gene.Proceedings of the National Academy of Sciences of the United States of America · 2003Article
- A new Drosophila spliceosomal intron position is common in plants.Proceedings of the National Academy of Sciences of the United States of America · 2003Article
- Molecular population genetics of Xdh and the evolution of base composition in Drosophila.Genetics · 2002Article
- Assessing the impact of comparative genomic sequence data on the functional annotation of the Drosophila genome.Genome biology · 2002Article
- Substitution rates in Drosophila nuclear genes: implications for translational selection.Genetics · 2001Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
We investigated the nucleotide composition of five genes, Xdh, Adh, Sod, Per, and 28SrRNA, in nine species of Drosophila (subgenus Sophophora) and one of Scaptodrosophila. The six species of the Drosophila saltans group markedly differ from the others in GC content and codon use bias. The GC content in the third codon position, and to a lesser extent in the first position and the introns, is higher in the D. melanogaster and D. obscura groups than in the D. saltans group (in Scaptodrosophila it is intermediate but closer to the melanogaster and obscura species). Differences are greater for Xdh than for Adh, Sod, Per, and 28SrRNA, which are functionally more constrained. We infer that rapid evolution of GC content in the saltans lineage is largely due to a shift in mutation pressure, which may have been associated with diminished natural selection due to smaller effective population numbers rather than reduced recombination rates. The rate of GC content evolution impacts the rate of protein evolution and may distort phylogenetic inferences. Previous observations suggesting that GC content evolution is very limited in Drosophila may have been distorted due to the restricted number of genes and species (mostly D. melanogaster) investigated.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.