ArticleBritish journal of cancer1999
Chromosomal aberrations in human hepatocellular carcinomas associated with hepatitis C virus infection detected by comparative genomic hybridization.
Article in British journal of cancer, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 73 citations in OpenAlex.
- Role of chromosome 1q copy number variation in hepatocellular carcinoma.World journal of hepatology · 2021Review
- SH3BGRL2 inhibits growth and metastasis in clear cell renal cell carcinoma via activating hippo/TEAD1-Twist1 pathway.EBioMedicine · 2020Article
- Characterization of human gastric adenocarcinoma cell lines established from peritoneal ascites.Oncology letters · 2018Article
- Difference of polymorphism VEGF-gene rs699947 in Indonesian chronic liver disease population.PloS one · 2017Article
- Methylation-regulated miR-124-1 suppresses tumorigenesis in hepatocellular carcinoma by targeting CASC3.Oncotarget · 2016Article
- Copy number gain of granulin-epithelin precursor (GEP) at chromosome 17q21 associates with overexpression in human liver cancer.BMC cancer · 2015Article
- Rsf-1 overexpression serves as a prognostic marker in human hepatocellular carcinoma.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014Article
- Recurrent genetic alterations in hepatitis C-associated hepatocellular carcinoma detected by genomic microarray: a genetic, clinical and pathological correlation study.Molecular cytogenetics · 2014Article
- Article
- The homeobox only protein homeobox (HOPX) and colorectal cancer.International journal of molecular sciences · 2013Review
- CHD1L Is a Marker for Poor Prognosis of Hepatocellular Carcinoma after Surgical Resection.Korean journal of pathology · 2013Article
- Hepatitis C virus inhibits DNA damage repair through reactive oxygen and nitrogen species and by interfering with the ATM-NBS1/Mre11/Rad50 DNA repair pathway in monocytes and hepatocytes.Journal of immunology (Baltimore, Md. : 1950) · 2010Article
- Chromosome 1q21 amplification and oncogenes in hepatocellular carcinoma.Acta pharmacologica Sinica · 2010Review
- Predominant modifier of extreme liver cancer susceptibility in C57BR/cdJ female mice localized to 6 Mb on chromosome 17.Carcinogenesis · 2009Article
- Malignant and benign ganglioglioma: a pathological and molecular study.Neuro-oncology · 2007Article
- Hepatocellular carcinoma pathogenesis: from genes to environment.Nature reviews. Cancer · 2006Review
- MYH Y165C and G382D mutations in hepatocellular carcinoma and cholangiocarcinoma patients.Journal of cancer research and clinical oncology · 2006Article
- Loss of HOP tumour suppressor expression in head and neck squamous cell carcinoma.British journal of cancer · 2004Article
- Amplification and overexpression of the EMS 1 oncogene, a possible prognostic marker, in human hepatocellular carcinoma.The Journal of molecular diagnostics : JMD · 2003Article
- Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thirty-five hepatocellular carcinomas (HCCs) associated with hepatitis C virus (HCV) were analysed by comparative genomic hybridization (CGH), to screen for changes in copy-number of DNA sequences. Chromosomal losses were noted in 1p34-36 (37%), 4q12-21 (48%), 5q13-21 (35%), 6q13-16 (23%), 8p21-23 (28%), 13q (20%), 16q (33%) and 17p13 (37%). Gains were noted in 1q (46%), 6p (20%), 8q21-24 (31%) and 17q (43%). High level gains indicative of gene amplifications were found in 7q31 (3%), 11q13 (3%), 14q12 (6%) and 17q12 (3%); amplification at 14q12 may be characteristic for HCCs. No significant difference in chromosomal aberrations was noted between carcinomas associated with HCV-infection in our study and those reported earlier in HCCs infected with hepatitis B virus (HBV), indicating that both HBV- and HCV-related carcinomas may progress through a similar cascade of molecular events.
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