Evidence map›Paper›PMID 10471049›Full record

ArticleBritish journal of cancer1999

Absence of mutations in the ATM gene in forty-seven cases of sporadic breast cancer.

D G Bebb, Z Yu, J Chen, M Telatar, K Gelmon, N Phillips, R A Gatti, B W Glickman

Abstract read
In one paragraph

Article in British journal of cancer, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Missense mutations but not allelic variants alter the function of ATM by dominant interference in patients with breast cancer.Proceedings of the National Academy of Sciences of the United States of America · 2002
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

D G BebbCentre for Environmental Health, Department of Biology, University of Victoria, Canada.
Z Yu
J Chen
M Telatar
K Gelmon
N Phillips
R A Gatti
B W Glickman

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epidemiological evidence points to an increased risk of breast cancer in ataxia telangiectasia (AT) heterozygote women. Previous attempts to screen early onset or familial breast cancer patients failed to confirm an association. The issue of AT and late onset sporadic breast cancer remained unresolved. We screened 47 women who developed later onset, sporadic breast cancer for ataxia telangiectasia mutated (ATM) mutations. No mutations were found.

Indexed as

Genetic Carrier ScreeningMutationProtein Serine-Threonine KinasesAdultAgedAge of OnsetAtaxia TelangiectasiaAtaxia Telangiectasia Mutated ProteinsBreast NeoplasmsCell Cycle ProteinsDNA-Binding ProteinsFemaleHumansMiddle AgedPolymerase Chain ReactionProteinsAtaxia Telangiectasia Mutated ProteinsATM protein, humanCell Cycle ProteinsDNA-Binding ProteinsProteinsProtein Serine-Threonine KinasesRNATumor Suppressor Proteins

Identifiers

PMID10471049
PMCPMC2363154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.