ReviewImmunologic research1999
Role of cytokines in pulmonary antimicrobial host defense.
Review in Immunologic research, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Cytokines Induced byBiomolecules · 2021Article
- HSP70-Homolog DnaK ofInternational journal of molecular sciences · 2020Article
- Monocyte Chemoattractant Protein-1, a Possible Biomarker of Multiorgan Failure and Mortality in Ventilator-Associated Pneumonia.International journal of molecular sciences · 2019Article
- Klebsiella pneumoniae infection biology: living to counteract host defences.FEMS microbiology reviews · 2019Review
- Interleukin-36γ and IL-36 receptor signaling mediate impaired host immunity and lung injury in cytotoxic Pseudomonas aeruginosa pulmonary infection: Role of prostaglandin E2.PLoS pathogens · 2017Article
- Probiotic strain Bacillus subtilis CU1 stimulates immune system of elderly during common infectious disease period: a randomized, double-blind placebo-controlled study.Immunity & ageing : I & A · 2015Article
- B cell-deficient mice display enhanced susceptibility to Paracoccidioides brasiliensis Infection.Mycopathologia · 2013Article
- Intrapulmonary G-CSF rescues neutrophil recruitment to the lung and neutrophil release to blood in Gram-negative bacterial infection in MCP-1-/- mice.Journal of immunology (Baltimore, Md. : 1950) · 2012Article
- Monocyte chemoattractant protein 1 regulates pulmonary host defense via neutrophil recruitment during Escherichia coli infection.Infection and immunity · 2011Article
- Autocrine effects of interleukin-6 mediate acute-phase proinflammatory and tissue-reparative transcriptional responses of canine bladder mucosa.Infection and immunity · 2011Article
- Article
- Klebsiella pneumoniae OmpA confers resistance to antimicrobial peptides.Antimicrobial agents and chemotherapy · 2009Article
- Alveolar epithelial STAT3, IL-6 family cytokines, and host defense during Escherichia coli pneumonia.American journal of respiratory cell and molecular biology · 2008Article
- Lung NF-kappaB activation and neutrophil recruitment require IL-1 and TNF receptor signaling during pneumococcal pneumonia.Journal of immunology (Baltimore, Md. : 1950) · 2005Article
- Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae.The Journal of experimental medicine · 2005Article
- Central role of toll-like receptor 4 signaling and host defense in experimental pneumonia caused by Gram-negative bacteria.Infection and immunity · 2005Article
- Impaired host defense to Klebsiella pneumoniae infection in mice treated with the PDE4 inhibitor rolipram.British journal of pharmacology · 2003Article
- Interleukin-18 impairs the pulmonary host response to Pseudomonas aeruginosa.Infection and immunity · 2003Article
- Cytokines in innate host defense in the lung.The Journal of clinical investigation · 2002Review
- Elevated cytokine and chemokine levels and prolonged pulmonary airflow resistance in a murine Mycoplasma pneumoniae pneumonia model: a microbiologic, histologic, immunologic, and respiratory plethysmographic profile.Infection and immunity · 2001Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Host defense of the lung is characterized by a fine balance between the generation of a vigorous inflammatory response to clear pathogens and maintenance of the integrity of the alveolar gas-exchange surface. The magnitude of the inflammatory response is therefore tightly regulated by pro- and anti-inflammatory cytokine mediators. This article summarizes current information on the roles of specific cytokines in pneumonia, with particular emphasis on ongoing investigations into the role of innate immunity in bacterial and fungal pneumonia.
Indexed as
Identifiers
10467980What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.