ArticleInfection and immunity1999
Coinfection with Toxoplasma gondii inhibits antigen-specific Th2 immune responses, tissue inflammation, and parasitism in BALB/c mice infected with Leishmania major.
Article in Infection and immunity, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 34 citations in OpenAlex.
- Previous Infection with Plasmodium berghei Confers Resistance to Toxoplasma gondii Infection in Mice.The Korean journal of parasitology · 2019Article
- Tegumentary leishmaniasis and coinfections other than HIV.PLoS neglected tropical diseases · 2018Review
- Experimental Toxoplasma gondii and Eimeria tenella co-infection in chickens.Parasitology research · 2017Article
- Chlamydial Pre-Infection Protects from Subsequent Herpes Simplex Virus-2 Challenge in a Murine Vaginal Super-Infection Model.PloS one · 2016Article
- Lymphocytic Choriomeningitis Virus Expands a Population of NKG2D+CD8+ T Cells That Exacerbates Disease in Mice Coinfected with Leishmania major.Journal of immunology (Baltimore, Md. : 1950) · 2015Article
- Polyparasitism is associated with increased disease severity in Toxoplasma gondii-infected marine sentinel species.PLoS neglected tropical diseases · 2011Article
- Article
- Coinfection is an important factor in epidemiological studies: the first serosurvey of the aoudad (Ammotragus lervia).European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2009Article
- Toxoplasma gondii infection blocks the development of allergic airway inflammation in BALB/c mice.Clinical and experimental immunology · 2009Article
- BALB/c mice resistant to Toxoplasma gondii infection proved to be highly susceptible when previously infected with Myocoptes musculinus fur mites.International journal of experimental pathology · 2007Article
- Involvement of the chemokine RANTES (CCL5) in resistance to experimental infection with Leishmania major.Infection and immunity · 2004Article
- Infection with Toxoplasma gondii reduces established and developing Th2 responses induced by Nippostrongylus brasiliensis infection.Infection and immunity · 2004Article
- Infection with Toxoplasma gondii increases atherosclerotic lesion in ApoE-deficient mice.Infection and immunity · 2004Article
- Coinfection with Borrelia burgdorferi and the agent of human granulocytic ehrlichiosis alters murine immune responses, pathogen burden, and severity of Lyme arthritis.Infection and immunity · 2001Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lesion size, cellular infiltration, and tissue parasitism in the footpads of BALB/c mice infected with Leishmania major were all dramatically inhibited during acute but not chronic infection with Toxoplasma gondii. Similarly, acute but not chronic toxoplasmosis at the time of infection with L. major had a strong inhibitory effect on development of acquired immune responses mediated by Th2 lymphocytes. In contrast, no major changes in Leishmania-specific Th1-mediated responses were observed in mice coinfected with T. gondii.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.