Evidence map›Paper›PMID 10447510›Full record

ArticleGenome research1999

High-resolution landmark framework for the sequence-ready mapping of Xq23-q26.1.

H E Steingruber, A Dunham, A J Coffey, S M Clegg, G R Howell, G L Maslen, C E Scott, R Gwilliam, P J Hunt, E C Sotheran and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Genome research, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

H E SteingruberThe Sanger Centre, Wellcome Trust Genome Campus, Hinxton, UK.
A Dunham
A J Coffey
S M Clegg
G R Howell
G L Maslen
C E Scott
R Gwilliam
P J Hunt
E C Sotheran
E J Huckle
S E Hunt
P Dhami
C Soderlund
M A Leversha
D R Bentley
M T Ross
Wellcome Sanger Institute · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

We have established a landmark framework map over 20-25 Mb of the long arm of the human X chromosome using yeast artificial chromosome (YAC) clones. The map has approximately one landmark per 45 kb of DNA and stretches from DXS7531 in proximal Xq23 to DXS895 in proximal Xq26, connecting to published framework maps on its proximal and distal sides. There are three gaps in the framework map resulting from the failure to obtain clone coverage from the YAC resources available. Estimates of the maximum sizes of these gaps have been obtained. The four YAC contigs have been positioned and oriented using somatic-cell hybrids and fluorescence in situ hybridization, and the largest is estimated to cover approximately 15 Mb of DNA. The framework map is being used to assemble a sequence-ready map in large-insert bacterial clones, as part of an international effort to complete the sequence of the X chromosome. PAC and BAC contigs currently cover 18 Mb of the region, and from these, 12 Mb of finished sequence is available.

Indexed as

Blotting, SouthernChromosome MappingChromosomes, Artificial, YeastContig MappingElectrophoresis, Gel, Pulsed-FieldFemaleGenetic MarkersHumansIn Situ Hybridization, FluorescenceSequence Analysis, DNAX ChromosomeGenetic Markers

Identifiers

PMID10447510
PMCPMC310799
OpenAlexW2123455996

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.