ArticleOncogene1999
Expression scanning of an array of growth control genes in human tumor cell lines.
Article in Oncogene, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- GATA3 Truncation Mutants Alter EMT Related Gene ExpressionFrontiers in genetics · 2022Article
- CRABP2 regulates invasion and metastasis of breast cancer through hippo pathway dependent on ER status.Journal of experimental & clinical cancer research : CR · 2019Article
- Genomic-Wide Analysis with Microarrays in Human Oncology.Microarrays (Basel, Switzerland) · 2015Review
- GATA3 inhibits breast cancer metastasis through the reversal of epithelial-mesenchymal transition.The Journal of biological chemistry · 2010Article
- A candidate molecular signature associated with tamoxifen failure in primary breast cancer.Breast cancer research : BCR · 2008Article
- Androgen-induced masculinization in rainbow trout results in a marked dysregulation of early gonadal gene expression profiles.BMC genomics · 2007Article
- An adaptation of the LMS method to determine expression variations in profiling data.Nucleic acids research · 2007Article
- FGFR1 and WT1 are markers of human prostate cancer progression.BMC cancer · 2006Article
- Feature extraction and signal processing for nylon DNA microarrays.BMC genomics · 2004Article
- Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters.Oncogene · 2004Article
- Distinct and complementary information provided by use of tissue and DNA microarrays in the study of breast tumor markers.The American journal of pathology · 2002Article
- Article
- Identification of potential diagnostic markers of prostate cancer and prostatic intraepithelial neoplasia using cDNA microarray.British journal of cancer · 2001Article
- Correlation between apoptosis microarray gene expression profiling and histopathological lymph node lesions.Molecular pathology : MP · 2001Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Analysis of gene expression on a medium- or large-scale is an increasingly recognized method for functional and clinical investigations based on the now extensive catalog of known or partially sequenced genes. The accessibility of this approach can be enhanced by using readily available technology (macroarrays on Nylon, radioactive detection) and the IMAGE resource to assemble sets of targets. We have set up such a medium-scale, flexible system and validated it by the study of quantitative expression levels for 120 genes in six cell lines, including three mammary carcinoma cell lines. A number of important parameters are identified as necessary for the assembly of a valid set and the obtention of good-quality quantitative data. The extensive data assembled in this survey identified potential targets of carcinogenesis, for example the CRABP2 and GATA3 transcription factor genes. We also demonstrate the feasibility of this procedure for relatively small tumor samples, without recourse to probe amplification methods.
Indexed as
Identifiers
10445855What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.