Evidence map›Paper›PMID 10441590›Full record

ArticleAmerican journal of human genetics1999

Combined use of biallelic and microsatellite Y-chromosome polymorphisms to infer affinities among African populations.

R Scozzari, F Cruciani, P Santolamazza, P Malaspina, A Torroni, D Sellitto, B Arredi, G Destro-Bisol, G De Stefano, O Rickards and 7 more

Abstract readComparative Study
In one paragraph

Article in American journal of human genetics, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Linguistic capacity was present in theFrontiers in psychology · 2025
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  12. Y-chromosomal evidence of a pastoralist migration through Tanzania to southern Africa.Proceedings of the National Academy of Sciences of the United States of America · 2008
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

R ScozzariDipartimento di Genetica e Biologia Molecolare, Università "La Sapienza", 00185, Rome, Italy. rscozzar@axcasp.caspur.it
F Cruciani
P Santolamazza
P Malaspina
A Torroni
D Sellitto
B Arredi
G Destro-Bisol
G De Stefano
O Rickards
C Martinez-Labarga
D Modiano
G Biondi
P Moral
A Olckers
D C Wallace
A Novelletto

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To define Y-chromosome haplotypes, we studied seven biallelic polymorphic sites. We combined data with those from four dinucleotide-repeat polymorphisms, to establish Y-chromosome compound superhaplotypes. Eight biallelic haplotypes that matched the dendrogram proposed by other investigators were identified in 762 Y chromosomes from 25 African populations. For each biallelic site, coalescence time of lineages carrying the derived allele was estimated and compared with previous estimates. The "ancestral" haplotype (haplotype 1A) was observed among Ethiopians, "Khoisan" (!Kung and Khwe), and populations from northern Cameroon. Microsatellite distributions within this haplotype showed that the Khoisan haplotypes 1A are widely divergent from those of the other two groups. Populations from northern Africa and northern Cameroon share a haplotype (i.e., 1C), which is not observed in other African populations but represents a major Eurasian cluster. Haplotypes 1C of northern Cameroon are clearly distinct from those of Europe, whereas haplotypes 1C of northern African are well intermingled with those of the other two groups. Apportionment of diversity for the Y-chromosomal biallelic haplotypes was calculated after populations were clustered into different configurations. Despite some correspondence between language affiliation and genetic similarity, geographic proximity seems to be a better predictor of genetic affinity.

Indexed as

AfricaAllelesBlack PeopleEuropeGene FrequencyGenetic VariationGeographyHaplotypesHumansLanguageMaleMicrosatellite RepeatsModels, GeneticPhylogenyPolymorphism, GeneticY Chromosome

Identifiers

PMID10441590
PMCPMC1377990

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.