ArticleAmerican journal of human genetics1999
Peopling of Sahul: mtDNA variation in aboriginal Australian and Papua New Guinean populations.
Article in American journal of human genetics, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 168 citations in OpenAlex.
- Anthropometric and metabolic differences and distribution of ABCG2 rs2231142 variant between lowland and highland Papuans in West Papua, Indonesia.Journal of physiological anthropology · 2025Article
- Population structure and migration in the Eastern Highlands of Papua New Guinea, a region impacted by the kuru epidemic.American journal of human genetics · 2024Article
- Advancements and Challenges in Ancient DNA Research: Bridging the Global North-South Divide.Genes · 2023Review
- Papua New Guinean Genomes Reveal the Complex Settlement of North Sahul.Molecular biology and evolution · 2021Article
- Landscape rules predict optimal superhighways for the first peopling of Sahul.Nature human behaviour · 2021Article
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- Aboriginal Australian mitochondrial genome variation - an increased understanding of population antiquity and diversity.Scientific reports · 2017Article
- Mitochondrial DNA diversity of present-day Aboriginal Australians and implications for human evolution in Oceania.Journal of human genetics · 2017Article
- Human settlement history between Sunda and Sahul: a focus on East Timor (Timor-Leste) and the Pleistocenic mtDNA diversity.BMC genomics · 2015Article
- Genome-wide insights into the genetic history of human populations.Investigative genetics · 2015Article
- Genome-wide data substantiate Holocene gene flow from India to Australia.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Denisova admixture and the first modern human dispersals into Southeast Asia and Oceania.American journal of human genetics · 2011Article
- Genomic screening by 454 pyrosequencing identifies a new human IGHV gene and sixteen other new IGHV allelic variants.Immunogenetics · 2011Article
- The role of genetic drift in shaping modern human cranial evolution: a test using microevolutionary modeling.International journal of evolutionary biology · 2011Article
- Ancient voyaging and Polynesian origins.American journal of human genetics · 2011Article
- Whole-genome genetic diversity in a sample of Australians with deep Aboriginal ancestry.American journal of human genetics · 2010Article
- India at the cross-roads of human evolution.Journal of biosciences · 2009Review
- The evolution and diversity of TNF block haplotypes in European, Asian and Australian Aboriginal populations.Genes and immunity · 2009Article
- Reconstructing Indian-Australian phylogenetic link.BMC evolutionary biology · 2009Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We examined genetic affinities of Aboriginal Australian and New Guinean populations by using nucleotide variation in the two hypervariable segments of the mtDNA control region (CR). A total of 318 individuals from highland Papua New Guinea (PNG), coastal PNG, and Aboriginal Australian populations were typed with a panel of 29 sequence-specific oligonucleotide (SSO) probes. The SSO-probe panel included five new probes that were used to type an additional 1,037 individuals from several Asian populations. The SSO-type data guided the selection of 78 individuals from Australia and east Indonesia for CR sequencing. A gene tree of these CR sequences, combined with published sequences from worldwide populations, contains two previously identified highland PNG clusters that do not include any Aboriginal Australians; the highland PNG clusters have coalescent time estimates of approximately 80,000 and 122,000 years ago, suggesting ancient isolation and genetic drift. SSO-type data indicate that 84% of the sample of PNG highlander mtDNA belong to these two clusters. In contrast, the Aboriginal Australian sequences are intermingled throughout the tree and cluster with sequences from multiple populations. Phylogenetic and multidimensional-scaling analyses of CR sequences and SSO types split PNG highland and Aboriginal Australian populations and link Aboriginal Australian populations with populations from the subcontinent of India. These mtDNA results do not support a close relationship between Aboriginal Australian and PNG populations but instead suggest multiple migrations in the peopling of Sahul.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.