Evidence map›Paper›PMID 10439832›Full record

ReviewMolecular pathology : MP1999

Demystified ... the polymerase chain reaction.

K R Baumforth, P N Nelson, J E Digby, J D O'Neil, P G Murray

Abstract readReview
In one paragraph

Review in Molecular pathology : MP, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Demystified. Human endogenous retroviruses.Molecular pathology : MP · 2003
    Review
  4. Demystified... Molecular pathology in oncology.Molecular pathology : MP · 2002
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

K R BaumforthBiomedical Research Laboratories, School of Health Sciences, University of Wolverhampton, UK.
P N Nelson
J E Digby
J D O'Neil
P G Murray

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since its initial description over twenty years ago the PCR has become one of the most valuable and flexible tools available to biomedical research. Subsequently, refinements and modifications to the basic approach, many of which have been described in this review, have enabled the application of the PCR to many areas of diagnostic medicine and have ensured its rapid acceptance as a routine test in many pathology disciplines. The growing importance of molecular approaches to the diagnosis of disease, particularly in histopathology, will continue to secure an ever expanding role for the PCR in diagnostic pathology.

Indexed as

DNADNA Mutational AnalysisHumansPolymerase Chain ReactionReverse Transcriptase Polymerase Chain ReactionSequence Analysis, DNADNA

Identifiers

PMID10439832
PMCPMC395663

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.