Commentary: a plausible model.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

8 citing papers in PubMed.

1. Molecular dynamics simulations suggest possible activation and deactivation pathways in the hERG channel.Communications biology · 2022
   Article
2. Spontaneous channel activity of the inositol 1,4,5-trisphosphate (InsP3) receptor (InsP3R). Application of allosteric modeling to calcium and InsP3 regulation of InsP3R single-channel gating.The Journal of general physiology · 2003
   Article
3. Gating mechanism of BK (Slo1) channels: so near, yet so far.The Journal of general physiology · 2003
   Review
4. Contribution of potential EF hand motifs to the calcium-dependent gating of a mouse brain large conductance, calcium-sensitive K(+) channel.The Journal of physiology · 2001
   Article
5. Integrated allosteric model of voltage gating of HCN channels.The Journal of general physiology · 2001
   Article
6. ATP regulation of recombinant type 3 inositol 1,4,5-trisphosphate receptor gating.The Journal of general physiology · 2001
   Article
7. Characterization of a calcium-regulation domain of the skeletal-muscle ryanodine receptor.The Biochemical journal · 2000
   Article
8. Voltage and Ca2+ activation of single large-conductance Ca2+-activated K+ channels described by a two-tiered allosteric gating mechanism.The Journal of general physiology · 2000
   Article

Corrections and comments

• Comment on
  Gating kinetics of single large-conductance Ca2+-activated K+ channels in high Ca2+ suggest a two-tiered allosteric gating mechanism.1999

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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