ArticleGenetics1999
Chromosome size-dependent control of meiotic reciprocal recombination in Saccharomyces cerevisiae: the role of crossover interference.
Article in Genetics, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
54 citing papers in PubMed.
- Effects of chromosome number reduction on mitotic and meiotic stability in fission yeast.Genome biology · 2025Article
- Keeping it safe: control of meiotic chromosome breakage.Trends in genetics : TIG · 2025Review
- Multiple independent losses of crossover interference during yeast evolutionary history.PLoS genetics · 2024Article
- Article
- Runs of homozygosity in the Italian goat breeds: impact of management practices in low-input systems.Genetics, selection, evolution : GSE · 2021Article
- Comprehensive mapping of transposable elements reveals distinct patterns of element accumulation on chromosomes of wild beetles.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2021Article
- Review
- Meiotic Crossover Patterning.Frontiers in cell and developmental biology · 2021Review
- New Solutions to Old Problems: Molecular Mechanisms of Meiotic Crossover Control.Trends in genetics : TIG · 2020Review
- Distinct Functions in Regulation of Meiotic Crossovers for DNA Damage Response Clamp Loader Rad24(Rad17) and Mec1(ATR) Kinase.Genetics · 2019Article
- Modulating Crossover Frequency and Interference for Obligate Crossovers inG3 (Bethesda, Md.) · 2017Article
- Widespread Impact of Chromosomal Inversions on Gene Expression Uncovers Robustness via Phenotypic Buffering.Molecular biology and evolution · 2016Article
- Genomic Landscape of Long Terminal Repeat Retrotransposons (LTR-RTs) and Solo LTRs as Shaped by Ectopic Recombination in Chicken and Zebra Finch.Journal of molecular evolution · 2016Article
- Article
- Global patterns of large copy number variations in the human genome reveal complexity in chromosome organization.Genetics research · 2015Article
- Modulating crossover positioning by introducing large structural changes in chromosomes.BMC genomics · 2015Article
- Comparative genomics reveals multiple genetic backgrounds of human pathogenicity in the Trypanosoma brucei complex.Genome biology and evolution · 2014Article
- Global linkage map connects meiotic centromere function to chromosome size in budding yeast.G3 (Bethesda, Md.) · 2013Article
- The modest beginnings of one genome project.Genetics · 2013Article
- Saccharomyces cerevisiae Dmc1 and Rad51 proteins preferentially function with Tid1 and Rad54 proteins, respectively, to promote DNA strand invasion during genetic recombination.The Journal of biological chemistry · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the yeast Saccharomyces cerevisiae, small chromosomes undergo meiotic reciprocal recombination (crossing over) at rates (centimorgans per kilobases) greater than those of large chromosomes, and recombination rates respond directly to changes in the total size of a chromosomal DNA molecule. This phenomenon, termed chromosome size-dependent control of meiotic reciprocal recombination, has been suggested to be important for ensuring that homologous chromosomes cross over during meiosis. The mechanism of this regulation was investigated by analyzing recombination in identical genetic intervals present on different size chromosomes. The results indicate that chromosome size-dependent control is due to different amounts of crossover interference. Large chromosomes have high levels of interference while small chromosomes have much lower levels of interference. A model for how crossover interference directly responds to chromosome size is presented. In addition, chromosome size-dependent control was shown to lower the frequency of homologous chromosomes that failed to undergo crossovers, suggesting that this control is an integral part of the mechanism for ensuring meiotic crossing over between homologous chromosomes.
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