ArticleJournal of biomolecular NMR1999
Refinement of the structure of protein-RNA complexes by residual dipolar coupling analysis.
Article in Journal of biomolecular NMR, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Conformational Investigations in Flexible Molecules Using Orientational NMR Constraints in Combination withMolecules (Basel, Switzerland) · 2019Article
- Applications of NMR to structure determination of RNAs large and small.Archives of biochemistry and biophysics · 2017Review
- GFT projection NMR for efficient (1)H/ (13)C sugar spin system identification in nucleic acids.Journal of biomolecular NMR · 2012Article
- Structure of a conserved retroviral RNA packaging element by NMR spectroscopy and cryo-electron tomography.Journal of molecular biology · 2010Article
- Major groove width variations in RNA structures determined by NMR and impact of 13C residual chemical shift anisotropy and 1H-13C residual dipolar coupling on refinement.Journal of biomolecular NMR · 2010Article
- Liquid-crystal NMR structure of HIV TAR RNA bound to its SELEX RNA aptamer reveals the origins of the high stability of the complex.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- Refined NMR structure of alpha-sarcin by 15N-1H residual dipolar couplings.European biophysics journal : EBJ · 2005Article
- Accurate measurement of 15N-13C residual dipolar couplings in nucleic acids.Journal of biomolecular NMR · 2005Article
- Pre-organized structure of viral DNA at the binding-processing site of HIV-1 integrase.Nucleic acids research · 2005Article
- Overall structure and sugar dynamics of a DNA dodecamer from homo- and heteronuclear dipolar couplings and 31P chemical shift anisotropy.Journal of biomolecular NMR · 2003Article
- Residual dipolar coupling constants and structure determination of large DNA duplexes.Journal of biomolecular NMR · 2002Article
- Structure-independent cross-validation between residual dipolar couplings originating from internal and external orienting media.Journal of biomolecular NMR · 2002Article
- MQ-hCN-based pulse sequences for the measurement of 13C1'-1H1', 13C1'-15N, 1H1'-15N, 13C1'-13C2', 1H1'-13C2',13C6/8-1H6/8, 13C6/8-15N, 1H6/8-15N, 13C6-13C5, 1H6-13C5 dipolar couplings in 13C, 15N-labeled DNA (and RNA).Journal of biomolecular NMR · 2002Article
- Application of dipolar coupling data to the refinement of the solution structure of the sarcin-ricin loop RNA.Journal of biomolecular NMR · 2001Article
- Measurement of 1H3'-31P dipolar couplings in a DNA oligonucleotide by constant-time NOESY difference spectroscopy.Journal of biomolecular NMR · 2001Article
- Lanthanide induced residual dipolar couplings for the conformational investigation of peripheral 15NH2 moieties.Journal of biomolecular NMR · 2000Article
- Assessment of molecular structure using frame-independent orientational restraints derived from residual dipolar couplings.Journal of biomolecular NMR · 2000Article
- The auto-orientation in high magnetic fields of oxidized cytochrome b562 as source of constraints for solution structure determination.Journal of biomolecular NMR · 2000Article
- A new approach for applying residual dipolar couplings as restraints in structure elucidation.Journal of biomolecular NMR · 2000Article
- RNA recognition by a Staufen double-stranded RNA-binding domain.The EMBO journal · 2000Article
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3 authors.
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Abstract
The main limitation in NMR-determined structures of nucleic acids and their complexes with proteins derives from the elongated, non-globular nature of physiologically important DNA and RNA molecules. Since it is generally not possible to obtain long-range distance constraints between distinct regions of the structure, long-range properties such as bending or kinking at sites of protein recognition cannot be determined accurately nor precisely. Here we show that use of residual dipolar couplings in the refinement of the structure of a protein-RNA complex improves the definition of the long-range properties of the RNA. These features are often an important aspect of molecular recognition and biological function; therefore, their improved definition is of significant value in RNA structural biology.
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