ReviewJournal of mammary gland biology and neoplasia1999
Apoptosis in the estrous and menstrual cycles.
Review in Journal of mammary gland biology and neoplasia, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 54 citations in OpenAlex.
- Transcriptomic Analysis of Pubertal and Adult Virgin Mouse Mammary Epithelial and Stromal Cell Populations.Journal of mammary gland biology and neoplasia · 2024Article
- The Cellular Organization of the Mammary Gland: Insights From Microscopy.Journal of mammary gland biology and neoplasia · 2021Review
- In-silico insights on the prognostic potential of immune cell infiltration patterns in the breast lobular epithelium.Scientific reports · 2016Article
- Relationship between histology, development and tumorigenesis of mammary gland in female rat.Experimental animals · 2016Review
- Hormonal Modulation of Breast Cancer Gene Expression: Implications for Intrinsic Subtyping in Premenopausal Women.Frontiers in oncology · 2016Review
- Efferocytosis creates a tumor microenvironment supportive of tumor survival and metastasis.Cancer cell & microenvironment · 2015Article
- Article
- Developmental stage and time dictate the fate of Wnt/β-catenin-responsive stem cells in the mammary gland.Cell stem cell · 2012Article
- Alterations in mast cell frequency and relationship to angiogenesis in the rat mammary gland during windows of physiologic tissue remodeling.Developmental dynamics : an official publication of the American Association of Anatomists · 2012Article
- Epithelial cell-directed efferocytosis in the post-partum mammary gland is necessary for tissue homeostasis and future lactation.BMC developmental biology · 2010Article
- Key stages in mammary gland development. Secretory activation in the mammary gland: it's not just about milk protein synthesis!Breast cancer research : BCR · 2007Review
- Assessment of the proliferative, apoptotic and cellular renovation indices of the human mammary epithelium during the follicular and luteal phases of the menstrual cycle.Breast cancer research : BCR · 2005Article
- Apoptosis regulation in the mammary gland.Cellular and molecular life sciences : CMLS · 2004Review
- Regulation of mammary gland branching morphogenesis by the extracellular matrix and its remodeling enzymes.Breast cancer research : BCR · 2004Review
- The POU homeodomain protein OCT3 as a potential transcriptional activator for fibroblast growth factor-4 (FGF-4) in human breast cancer cells.The Biochemical journal · 2003Article
- Establishing a framework for the functional mammary gland: from endocrinology to morphology.Journal of mammary gland biology and neoplasia · 2002Review
- An atlas of mouse mammary gland development.Journal of mammary gland biology and neoplasia · 2000Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
In the absence of pregnancy, the adult mammary gland is subjected to cyclic fluctuations of hormonal stimulation that constitute the estrous and menstrual cycles. The mammary epithelium responds to these systemic hormonal changes by regional proliferation, differentiation and cell death by apoptosis. The fact that the mammary epithelial response involves only a minor subset of the epithelial cells implies a delicate local control of epithelial cell fate resulting in either cell death or survival. Evidence gleaned from descriptive data suggests that the apoptosis-related genes of the Bcl-2 gene family, tissue remodeling genes, protein tyrosine kinases and master genes of the homeotic gene cluster may be involved in determining epithelial cell fate during the estrous cycle.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.