ReviewBrain pathology (Zurich, Switzerland)1999
Human neural stem cells: isolation, expansion and transplantation.
Review in Brain pathology (Zurich, Switzerland), 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evaluation of the Clinical Efficacy of Stem Cell Transplantation in the Treatment of Spinal Cord Injury: A Systematic Review and Meta-analysis.Cell transplantationPooled it
- Clinical Trial of Human Fetal Brain-Derived Neural Stem/Progenitor Cell Transplantation in Patients with Traumatic Cervical Spinal Cord Injury.Neural plasticity · 2015Trial
- Sphere-Based Expansion of Myogenic Progenitors from Human Pluripotent Stem Cells.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Functional bioengineered models of the central nervous system.Nature reviews bioengineering · 2023Review
- The universal stem cell.Leukemia · 2022Review
- Isolation and Culture of Neural Stem/Progenitor Cells from the Postnatal Periventricular Region.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Regeneration of sciatic nerves by transplanted microvesicles of human neural stem cells derived from embryonic stem cells.Cell and tissue banking · 2020Article
- Development of glial restricted human neural stem cells for oligodendrocyte differentiation in vitro and in vivo.Scientific reports · 2019Article
- ATR kinase inhibitors NVP-BEZ235 and AZD6738 effectively penetrate the brain after systemic administration.Radiation oncology (London, England) · 2018Article
- Human Neural Stem Cells with GDNF Site-Specific Integration at AAVS1 by Using AAV Vectors Retained Their Stemness.Neurochemical research · 2018Article
- Efficient Generation of Viral and Integration-Free Human Induced Pluripotent Stem Cell-Derived Oligodendrocytes.Current protocols in stem cell biology · 2016Article
- Engineering Stem Cells for Biomedical Applications.Advanced healthcare materials · 2016Review
- Development of stem cell-based therapy for Parkinson's disease.Translational neurodegeneration · 2015Article
- Elevated cell invasion in a tumor sphere culture of RSV-M mouse glioma cells.Neurologia medico-chirurgica · 2015Article
- Stem cells for brain repair in neonatal hypoxia-ischemia.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2014Review
- Hydrogel formulation determines cell fate of fetal and adult neural progenitor cells.Stem cell research · 2014Article
- Process-based expansion and neural differentiation of human pluripotent stem cells for transplantation and disease modeling.Journal of neuroscience research · 2013Article
- Migration, integration, survival, and differentiation of stem cell-derived neural progenitors in the retina in a pharmacological model of retinal degeneration.ISRN ophthalmology · 2013Article
- Derivation of autism spectrum disorder-specific induced pluripotent stem cells from peripheral blood mononuclear cells.Neuroscience letters · 2012Article
- Neural stem cell transplantation as a therapeutic approach for treating lysosomal storage diseases.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Neural stem cells, with the capacity to self renew and produce the major cell types of the brain, exist in the developing and adult rodent central nervous system (CNS). Their exact function and distribution is currently being assessed, but they represent an interesting cell population, which may be used to study factors important for the differentiation of neurons, astrocytes and oligodendrocytes. Recent evidence suggests that neural stem cells may also exist in both the developing and adult human CNS. These cells can be grown in vitro for long periods of time while retaining the potential to differentiate into nervous tissue. Significantly, many neurons can be produced from a limited number of starting cells, raising the possibility of cell replacement therapy for a wide range of neurological disorders. This review summarises this fascinating and growing field of neurobiology, with a particular focus on human tissues.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.