ArticleJournal of clinical microbiology1999
Helicobacter pylori infection in indigenous families of Central America: serostatus and oral and fingernail carriage.
Article in Journal of clinical microbiology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 86 citations in OpenAlex.
- Clinical significance of a possible route of transmission ofWorld journal of gastrointestinal pathophysiology · 2026Article
- Article
- Helicobacter pylori Infection Promotes Gastric Premalignancies and Malignancies Lesions and Demotes Hyperplastic Polyps: A 5 Year Multicentric Study among Cameroonian Dyspeptic Patients.Asian Pacific journal of cancer prevention : APJCP · 2023Article
- Seroprevalence ofThe American journal of tropical medicine and hygiene · 2020Article
- Identification ofJournal of pharmacy & bioallied sciences · 2019Article
- Potential risk factors and prevalence of Helicobacter pylori infection among adult patients with dyspepsia symptoms in Cameroon.BMC infectious diseases · 2018Article
- Seroprevalence of Helicobacter pylori in Hispanics living in Puerto Rico: A population-based study.Helicobacter · 2018Article
- Are the view of Helicobacter pylori colonized in the oral cavity an illusion?Experimental & molecular medicine · 2017Review
- The investigation of Helicobacter pylori in the dental biofilm and saliva samples of children with dyspeptic complaints.BMC oral health · 2017Article
- Role of dental plaque, saliva and periodontal disease in Helicobacter pylori infection.World journal of gastroenterology · 2014Review
- An association between Helicobacter pylori and upper respiratory tract disease: fact or fiction?World journal of gastroenterology · 2014Review
- Oral Cavity as an Extragastric Reservoir of Helicobacter pylori.ISRN gastroenterology · 2014Review
- The Role of Helicobacter pylori in Upper Respiratory System Infections: Is it More Than Colonization?Current infectious disease reports · 2012Article
- Helicobacter pylori: a poor man's gut pathogen?Gut pathogens · 2010Article
- PCR-based diagnosis of Helicobacter pylori infection and real-time determination of clarithromycin resistance directly from human gastric biopsy samples.Journal of clinical microbiology · 2001Article
- Helicobacter pylori: clonal population structure and restricted transmission within families revealed by molecular typing.Journal of clinical microbiology · 2000Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Helicobacter pylori infection remains one of the most common in humans, but the route of transmission of the bacterium is still uncertain. This study was designed to elucidate possible sources of infection in an isolated, rural population in Guatemala. A total of 242 subjects in family units participated in the study. A medical history, including a history of dyspepsia, was taken by a physician and immunoglobulin G antibodies to H. pylori were detected with the QuickVue (Quidel, San Diego, Calif.) onsite serology test. Overall, 58% of subjects were seropositive, with a positive relationship between mother and child (P = 0.02) and a positive correlation between the serostatuses of siblings (intraclass correlation coefficient = 0.63). There was no association between serostatus and gastric symptoms. Oral H. pylori was detected from periodontal pockets of various depths and the dorsum of the tongue by nested PCR. Eighty-seven percent of subjects had at least one oral site positive for H. pylori, with the majority of subjects having multiple positive sites. There was no association between periodontal pocket depth and the detection of H. pylori. Nested PCR was also used to detect H. pylori from beneath the nail of the index finger of each subject's dominant hand. Overall, 58% of subjects had a positive fingernail result, with a significant positive relationship between fingernail and tongue positivity (P = 0.002). In conclusion, the results of this study suggest that oral carriage of H. pylori may play a role in the transmission of infection and that the hand may be instrumental in transmission.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.