ArticleJournal of virology1999
The integration machinery of ZAM, a retroelement from Drosophila melanogaster, acts as a sequence-specific endonuclease.
Article in Journal of virology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Transposable element profiles reveal cell line identity and loss of heterozygosity in Drosophila cell culture.Genetics · 2021Article
- Article
- Drosophila errantiviruses.Mobile genetic elements · 2012Article
- Article
- Functional characteristics of a highly specific integrase encoded by an LTR-retrotransposon.PloS one · 2008Article
- Promoter competition as a mechanism of transcriptional interference mediated by retrotransposons.The EMBO journal · 2002Article
- Coupling of enhancer and insulator properties identified in two retrotransposons modulates their mutagenic impact on nearby genes.Molecular and cellular biology · 2002Article
- Impact of multiple insertions of two retroelements, ZAM and Idefix at an euchromatic locus.Genetica · 2000Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Retroviruses and retrotransposons insert into the host genome with no obvious sequence specificity. We examined the target sites of the retroelement ZAM by sequencing each host-ZAM junction in the genome of Drosophila melanogaster. Our overall data provide compelling evidence that ZAM integration machinery recognizes and leads to ZAM insertion into the sequence 5'-GCGCGCg-3'. This unique property of ZAM will facilitate the development of new tools to study the integration process of retroelements.
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Registered trials
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