ArticleJournal of virology1999
Three-dimensional structure of Aleutian mink disease parvovirus: implications for disease pathogenicity.
Article in Journal of virology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 83 citations in OpenAlex.
- Article
- Molecular characterization of emerging chicken and turkey parvovirus variants and novel strains in Guangxi, China.Scientific reports · 2023Article
- Capsid Structure of Aleutian Mink Disease Virus and Human Parvovirus 4: New Faces in the Parvovirus Family Portrait.Viruses · 2022Article
- Natural disease and evolution of an Amdoparvovirus endemic in striped skunks (Mephitis mephitis).Transboundary and emerging diseases · 2022Article
- A new perspective on the evolution and diversity of the genusVirus evolution · 2022Article
- Review
- Genetic characterization of the complete genome of an Aleutian mink disease virus isolated in north China.Virus genes · 2016Article
- Mapping Antigenic Epitopes on the Human Bocavirus Capsid.Journal of virology · 2016Article
- Driving forces behind the evolution of the Aleutian mink disease parvovirus in the context of intensive farming.Virus evolution · 2016Article
- Perspective on Adeno-Associated Virus Capsid Modification for Duchenne Muscular Dystrophy Gene Therapy.Human gene therapy · 2015Review
- Role of capsid proteins in parvoviruses infection.Virology journal · 2015Review
- Structure of an enteric pathogen, bovine parvovirus.Journal of virology · 2015Article
- Adeno-associated virus serotype 1 (AAV1)- and AAV5-antibody complex structures reveal evolutionary commonalities in parvovirus antigenic reactivity.Journal of virology · 2015Article
- Amdoparvoviruses in small mammals: expanding our understanding of parvovirus diversity, distribution, and pathology.Frontiers in microbiology · 2015Review
- Phylogenetic analysis of the VP2 gene of Aleutian mink disease parvoviruses isolated from 2009 to 2011 in China.Virus genes · 2012Article
- Molecular epidemiology of Aleutian disease virus in free-ranging domestic, hybrid, and wild mink.Evolutionary applications · 2012Article
- Human bocavirus capsid structure: insights into the structural repertoire of the parvoviridae.Journal of virology · 2010Article
- The capsid proteins of Aleutian mink disease virus activate caspases and are specifically cleaved during infection.Journal of virology · 2010Article
- Minute virus of mice, a parvovirus, in complex with the Fab fragment of a neutralizing monoclonal antibody.Journal of virology · 2007Article
- Surface-exposed adeno-associated virus Vp1-NLS capsid fusion protein rescues infectivity of noninfectious wild-type Vp2/Vp3 and Vp3-only capsids but not that of fivefold pore mutant virions.Journal of virology · 2007Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
Abstract
The three-dimensional structure of expressed VP2 capsids of Aleutian mink disease parvovirus strain G (ADVG-VP2) has been determined to 22 A resolution by cryo-electron microscopy and image reconstruction techniques. A structure-based sequence alignment of the VP2 capsid protein of canine parvovirus (CPV) provided a means to construct an atomic model of the ADVG-VP2 capsid. The ADVG-VP2 reconstruction reveals a capsid structure with a mean external radius of 128 A and several surface features similar to those found in human parvovirus B19 (B19), CPV, feline panleukopenia virus (FPV), and minute virus of mice (MVM). Dimple-like depressions occur at the icosahedral twofold axes, canyon-like regions encircle the fivefold axes, and spike-like protrusions decorate the threefold axes. These spikes are not present in B19, and they are more prominent in ADV compared to the other parvoviruses owing to the presence of loop insertions which create mounds near the threefold axes. Cylindrical channels along the fivefold axes of CPV, FPV, and MVM, which are surrounded by five symmetry-related beta-ribbons, are closed in ADVG-VP2 and B19. Immunoreactive peptides made from segments of the ADVG-VP2 capsid protein map to residues in the mound structures. In vitro tissue tropism and in vivo pathogenic properties of ADV map to residues at the threefold axes and to the wall of the dimples.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.