ArticleMolecular biology of the cell1999
The plant vesicle-associated SNARE AtVTI1a likely mediates vesicle transport from the trans-Golgi network to the prevacuolar compartment.
Article in Molecular biology of the cell, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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51 citing papers in PubMed, 120 citations in OpenAlex.
- Creeping Stem 1 regulates directional auxin transport for lodging resistance in soybean.Plant biotechnology journal · 2025Article
- Cellular and physiological functions of SGR family in gravitropic response in higher plants.Journal of advanced research · 2025Review
- High-density genetic map construction and QTL mapping of a zigzag-shaped stem trait in tea plant (Camellia sinensis).BMC plant biology · 2024Article
- Domestication over Speciation in Allopolyploid Cotton Species: A Stronger Transcriptomic Pull.Genes · 2023Article
- Genome-Wide Identification and Expression Analysis of SNARE Genes inPlants (Basel, Switzerland) · 2022Article
- Transcriptome and metabolite analyses provide insights into zigzag-shaped stem formation in tea plants (Camellia sinensis).BMC plant biology · 2020Article
- Vesicle Transport in Plants: A Revised Phylogeny of SNARE Proteins.Evolutionary bioinformatics online · 2020Article
- Turnip Mosaic Virus Uses the SNARE Protein VTI11 in an Unconventional Route for Replication Vesicle Trafficking.The Plant cell · 2018Article
- Variation in Membrane Trafficking Linked to SNARE AtSYP51 Interaction With Aquaporin NIP1;1.Frontiers in plant science · 2018Article
- SCYL2 Genes Are Involved in Clathrin-Mediated Vesicle Trafficking and Essential for Plant Growth.Plant physiology · 2017Article
- Isonitrosoacetophenone drives transcriptional reprogramming in Nicotiana tabacum cells in support of innate immunity and defense.PloS one · 2015Article
- SNARE VTI13 plays a unique role in endosomal trafficking pathways associated with the vacuole and is essential for cell wall organization and root hair growth in arabidopsis.Annals of botany · 2014Article
- Identification of trans-golgi network proteins in Arabidopsis thaliana root tissue.Journal of proteome research · 2014Article
- Plant vacuole morphology and vacuolar trafficking.Frontiers in plant science · 2014Review
- Functional redundancy between trans-Golgi network SNARE family members in Arabidopsis thaliana.BMC biochemistry · 2013Article
- Comparative analysis of latex transcriptome reveals putative molecular mechanisms underlying super productivity of Hevea brasiliensis.PloS one · 2013Article
- Multiple roles for membrane-associated protein trafficking and signaling in gravitropism.Frontiers in plant science · 2012Article
- Homomeric interaction of AtVSR1 is essential for its function as a vacuolar sorting receptor.Plant physiology · 2010Article
- Auxin-mediated ribosomal biogenesis regulates vacuolar trafficking in Arabidopsis.The Plant cell · 2010Article
- Loss-of-function mutations of retromer large subunit genes suppress the phenotype of an Arabidopsis zig mutant that lacks Qb-SNARE VTI11.The Plant cell · 2010Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Membrane traffic in eukaryotic cells relies on recognition between v-SNAREs on transport vesicles and t-SNAREs on target membranes. Here we report the identification of AtVTI1a and AtVTI1b, two Arabidopsis homologues of the yeast v-SNARE Vti1p, which is required for multiple transport steps in yeast. AtVTI1a and AtVTI1b share 60% amino acid identity with one another and are 32 and 30% identical to the yeast protein, respectively. By suppressing defects found in specific strains of yeast vti1 temperature-sensitive mutants, we show that AtVTI1a can substitute for Vti1p in Golgi-to-prevacuolar compartment (PVC) transport, whereas AtVTI1b substitutes in two alternative pathways: the vacuolar import of alkaline phosphatase and the so-called cytosol-to-vacuole pathway used by aminopeptidase I. Both AtVTI1a and AtVTI1b are expressed in all major organs of Arabidopsis. Using subcellular fractionation and immunoelectron microscopy, we show that AtVTI1a colocalizes with the putative vacuolar cargo receptor AtELP on the trans-Golgi network and the PVC. AtVTI1a also colocalizes with the t-SNARE AtPEP12p to the PVC. In addition, AtVTI1a and AtPEP12p can be coimmunoprecipitated from plant cell extracts. We propose that AtVTI1a functions as a v-SNARE responsible for targeting AtELP-containing vesicles from the trans-Golgi network to the PVC, and that AtVTI1b is involved in a different membrane transport process.
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