ArticleClinical and diagnostic laboratory immunology1999
Serological diagnosis of human cysticercosis by use of recombinant antigens from Taenia solium cysticerci.
Article in Clinical and diagnostic laboratory immunology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 38 citations in OpenAlex.
- An isolated subcutaneous paraspinal pseudo-tumor-more to it than meets the eye-a case report and review of literature.Journal of surgical case reports · 2023Article
- Triplex ELISA for Assessing Durability of Taenia solium Seropositivity after Neurocysticercosis Cure.Emerging infectious diseases · 2023Article
- Cysticercus of the Breast which Mimicked a Fibroadenoma: A Rare Presentation.Journal of clinical and diagnostic research : JCDR · 2012Article
- Serological diagnosis of echinococcosis: the diagnostic potential of native antigens.Infection · 2012Article
- Evaluation of lower molecular mass (20-24 kDa) Taenia solium cysticercus antigen fraction by ELISA and dot blot for the serodiagnosis of neurocysticercosis in children.Parasitology research · 2008Article
- Evaluation of recombinant HP6-Tsag, an 18 kDa Taenia saginata oncospheral adhesion protein, for the diagnosis of cysticercosis.Parasitology research · 2007Article
- Identification of a diagnostic antibody-binding region on the immunogenic protein EpC1 from Echinococcus granulosus and its application in population screening for cystic echinococcosis.Clinical and experimental immunology · 2007Article
- Characterization of the 8-kilodalton antigens of Taenia solium metacestodes and evaluation of their use in an enzyme-linked immunosorbent assay for serodiagnosis.Journal of clinical microbiology · 2003Article
- Neurocysticercosis--New Millennium, ancient disease and unending debate.Indian journal of pediatrics · 2003Review
- Molecular characterization and diagnostic value of Taenia solium low-molecular-weight antigen genes.Journal of clinical microbiology · 2000Article
- Isolated intramuscular cysticercosis: Clinicopathological features, diagnosis and management - A review.Journal of clinical orthopaedics and traumaReview
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A Taenia solium metacestode cDNA expression library in the lambda ZAPII vector was screened with pooled sera from patients with neurocysticercosis. Sixty primary clones were identified and shown to belong to two classes. The clones NC-3 and NC-9 did not reveal any significant homologies to sequences deposited in the databases and were further characterized. Both recombinant antigens were expressed as glutathione S-transferase fusion proteins and applied for serological diagnosis of human cysticercosis. An enzyme-linked immunosorbent assay was established and evaluated with 27 serum samples of La Réunion and Madagascar patients with cysticercosis. Diagnosis in these patients was established with radiological and serological procedures. For antigen NC-3 a sensitivity of 96.3% and a specificity of 91.5% for the serodiagnosis were achieved. In contrast, the sensitivity of antigen NC-9 was only 33.3%.
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