ReviewAntimicrobial agents and chemotherapy1999
Why metronidazole is active against both bacteria and parasites.
Review in Antimicrobial agents and chemotherapy, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
70 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Clinical pharmacokinetics of metronidazole: a systematic review and meta-analysis.Antimicrobial agents and chemotherapy · 2025Pooled it
- Efficacy of 5-nitroimidazoles for the treatment of giardiasis: a systematic review of randomized controlled trials.PLoS neglected tropical diseases · 2014Pooled it
- Evaluating metronidazole as a novel, safe CYP2A6 phenotyping probe in healthy adults.British journal of clinical pharmacology · 2019Trial
- A high-confidence inventory of the proteins in the mitochondrion-related organelle of Giardia.Current biology : CB · 2026Article
- Article
- P. gingivalis-host interactions direct antibiotic adjuvants for periodontitis antimicrobial therapy.International journal of oral science · 2026Article
- Genotype-Specific Small EVs Released by Giardia lamblia Act as Mediators of Phenotypic Adaptation Under Metronidazole-Induced Stress.Journal of extracellular vesicles · 2025Article
- Use, Risk and Revalorization of Veterinary Antibiotics: A Canadian Perspective.Antibiotics (Basel, Switzerland) · 2025Review
- Gut Microbiota in a Viral Model of Multiple Sclerosis: Modulation and Pitfalls by Oral Antibiotic Treatment.Cells · 2025Article
- Treatment of giardiasis in dogs: field clinical study to confirm the efficacy, safety, and acceptance of a metronidazole-based flavored oral suspension.Parasites & vectors · 2025Article
- Metronidazole Activation by a Deeply Entangled Dimeric Malic Enzyme inPathogens (Basel, Switzerland) · 2025Article
- Rethinking central nervous system sparganosis: Beyond surgical cure toward integrated immune-parasitic surveillance.Surgical neurology international · 2025Article
- Antimicrobial resistance and natural alternatives:Frontiers in veterinary science · 2025Article
- Disseminated and migratory sparganosis in the central nervous system: A case report and literature review of combined spinal and intracranial involvement.Surgical neurology international · 2025Article
- Modern Technologies inSovremennye tekhnologii v meditsine · 2025Review
- Bacteriophage FNU1 negatesFrontiers in cellular and infection microbiology · 2025Article
- Current and Ongoing Developments in TargetingMicroorganisms · 2024Review
- Demodicosis in Different Age Groups and Alternative Treatment Options-A Review.Journal of clinical medicine · 2023Review
- Distinct features of the host-parasite interactions between nonadherent and adherent Trichomonas vaginalis isolates.PLoS neglected tropical diseases · 2023Article
- Comparison of in vitro Killing Effect of Thai Herbal Essential Oils, Tea Tree Oil, and Metronidazole 0.75% versus Ivermectin 1% onClinical, cosmetic and investigational dermatology · 2023Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.