ArticleGenetics1999
DNA sequence and functional analysis of homologous ARS elements of Saccharomyces cerevisiae and S. carlsbergensis.
Article in Genetics, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 24 citations in OpenAlex.
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- Conservation of a DNA Replication Motif among Phylogenetically Distant Budding Yeast Species.Genome biology and evolution · 2021Article
- The dynamic nature of the human origin recognition complex revealed through five cryoEM structures.eLife · 2020Article
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- The dynamics of genome replication using deep sequencing.Nucleic acids research · 2014Article
- Conservation of replication timing reveals global and local regulation of replication origin activity.Genome research · 2012Article
- Linear derivatives of Saccharomyces cerevisiae chromosome III can be maintained in the absence of autonomously replicating sequence elements.Molecular and cellular biology · 2007Article
- Genome-wide identification of replication origins in yeast by comparative genomics.Genes & development · 2006Article
- A new reversion assay for measuring all possible base pair substitutions in Saccharomyces cerevisiae.Genetics · 2005Article
- Prediction of Saccharomyces cerevisiae replication origins.Genome biology · 2004Article
- Completion of replication map of Saccharomyces cerevisiae chromosome III.Molecular biology of the cell · 2001Article
- Two compound replication origins in Saccharomyces cerevisiae contain redundant origin recognition complex binding sites.Molecular and cellular biology · 2001Article
- Restriction of ectopic recombination by interhomolog interactions during Saccharomyces cerevisiae meiosis.Proceedings of the National Academy of Sciences of the United States of America · 2000Article
- Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
ARS elements of Saccharomyces cerevisiae are the cis-acting sequences required for the initiation of chromosomal DNA replication. Comparisons of the DNA sequences of unrelated ARS elements from different regions of the genome have revealed no significant DNA sequence conservation. We have compared the sequences of seven pairs of homologous ARS elements from two Saccharomyces species, S. cerevisiae and S. carlsbergensis. In all but one case, the ARS308-ARS308(carl) pair, significant blocks of homology were detected. In the cases of ARS305, ARS307, and ARS309, previously identified functional elements were found to be conserved in their S. carlsbergensis homologs. Mutation of the conserved sequences in the S. carlsbergensis ARS elements revealed that the homologous sequences are required for function. These observations suggested that the sequences important for ARS function would be conserved in other ARS elements. Sequence comparisons aided in the identification of the essential matches to the ARS consensus sequence (ACS) of ARS304, ARS306, and ARS310(carl), though not of ARS310.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.