ArticleGenetics1999
Conservation of ARS elements and chromosomal DNA replication origins on chromosomes III of Saccharomyces cerevisiae and S. carlsbergensis.
Article in Genetics, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 10 citations in OpenAlex.
- The reference genome sequence of Saccharomyces cerevisiae: then and now.G3 (Bethesda, Md.) · 2014Article
- Maintaining replication origins in the face of genomic change.Genome research · 2012Article
- From sequence to function: Insights from natural variation in budding yeasts.Biochimica et biophysica acta · 2011Review
- Fragile genomic sites are associated with origins of replication.Genome biology and evolution · 2009Article
- Linear derivatives of Saccharomyces cerevisiae chromosome III can be maintained in the absence of autonomously replicating sequence elements.Molecular and cellular biology · 2007Article
- Article
- A function for subtelomeric DNA in Saccharomyces cerevisiae.Genetics · 2003Article
- Two compound replication origins in Saccharomyces cerevisiae contain redundant origin recognition complex binding sites.Molecular and cellular biology · 2001Article
- DNA sequence and functional analysis of homologous ARS elements of Saccharomyces cerevisiae and S. carlsbergensis.Genetics · 1999Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
DNA replication origins, specified by ARS elements in Saccharomyces cerevisiae, play an essential role in the stable transmission of chromosomes. Little is known about the evolution of ARS elements. We have isolated and characterized ARS elements from a chromosome III recovered from an alloploid Carlsberg brewing yeast that has diverged from its S. cerevisiae homeologue. The positions of seven ARS elements identified in this S. carlsbergensis chromosome are conserved: they are located in intergenic regions flanked by open reading frames homologous to those that flank seven ARS elements of the S. cerevisiae chromosome. The S. carlsbergensis ARS elements were active both in S. cerevisiae and S. monacensis, which has been proposed to be the source of the diverged genome present in brewing yeast. Moreover, their function as chromosomal replication origins correlated strongly with the activity of S. cerevisiae ARS elements, demonstrating the conservation of ARS activity and replication origin function in these two species.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.