ReviewOncogene1999
Reassessing the role of C-MYB in tumorigenesis.
Review in Oncogene, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 44 citations in OpenAlex.
- MYB sustains hypoxic survival of pancreatic cancer cells by facilitating metabolic reprogramming.EMBO reports · 2023Article
- Immunohistochemical study of PUMA, c-Myb and p53 expression in the benign and malignant lesions of gallbladder and their clinicopathological significances.International journal of clinical oncology · 2013Article
- Cyclophilin B as a co-regulator of prolactin-induced gene expression and function in breast cancer cells.Journal of molecular endocrinology · 2010Article
- c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis.The Journal of clinical investigation · 2010Article
- Role of c-Myb during prolactin-induced signal transducer and activator of transcription 5a signaling in breast cancer cells.Endocrinology · 2009Article
- Expression of cyclophilin B is associated with malignant progression and regulation of genes implicated in the pathogenesis of breast cancer.The American journal of pathology · 2009Article
- Regulating gene expression in human leukemia cells using light-activated oligodeoxynucleotides.Nucleic acids research · 2008Article
- c-Myb is an essential downstream target for homeobox-mediated transformation of hematopoietic cells.Blood · 2006Article
- En masse nascent transcription analysis to elucidate regulatory transcription factors.Nucleic acids research · 2006Article
- Chromosome 6 abnormalities correlated with thymoma progression.The American journal of pathology · 2003Article
- The transformation suppressor protein Pdcd4 shuttles between nucleus and cytoplasm and binds RNA.Oncogene · 2003Article
- A novel yeast system for in vivo selection of recognition sequences: defining an optimal c-Myb-responsive element.Nucleic acids research · 2001Article
- Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis.Molecular and cellular biology · 2001Article
- Article
- Acetylation of histones and transcription-related factors.Microbiology and molecular biology reviews : MMBR · 2000Review
- HTLV-I Tax transrepresses the human c-Myb promoter independently of its interaction with CBP or p300.Oncogene · 2000Article
- Article
- c-Myb acetylation at the carboxyl-terminal conserved domain by transcriptional co-activator p300.Oncogene · 2000Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hematopoietic tumors in both humans and mice frequently up-regulate expression of the c-myb gene, but it is unclear whether this is a cause or a consequence of the leukemic state. Recent results placing super-activation of the c-Myb protein at the bottom of a kinase-activated signal transduction pathway indicate that it may be a downstream effector of transformation induced by other oncogenes. The relationship between c-Myb and the serine-threonine kinase pim-1, its immediate activator, is discussed, together with the possibility that c-Myb, like pim-1, may be able to synergize with c-Myc to induce tumors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.