ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience1999
Spatial attention deficits in patients with acquired or developmental cerebellar abnormality.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
79 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Cerebellar Cognitive Affective Syndrome-a Meta-analysis.Cerebellum (London, England) · 2019Pooled it
- A novel approach to training attention and gaze in ASD: A feasibility and efficacy pilot study.Developmental neurobiology · 2018Trial
- Assessing the molecular genetics of attention networks.BMC neuroscience · 2002Trial
- Assessing the heritability of attentional networks.BMC neuroscience · 2001Trial
- Bridging cognitive reserve and cerebellar networks: counteracting brain damage in patients with Alzheimer's disease at different clinical stages.Frontiers in cellular neuroscience · 2026Article
- Altered prefrontal and cerebellar parvalbumin neuron counts are associated with cognitive changes in male rats.Experimental brain research · 2024Article
- Sex Differences and Behavioral Associations with Typically Developing Pediatric Regional Cerebellar Gray Matter Volume.Cerebellum (London, England) · 2024Article
- Cerebellar Transcranial Magnetic Stimulation (TMS) Impairs Visual Working Memory.Cerebellum (London, England) · 2023Article
- Networking of the Human Cerebellum: From Anatomo-Functional Development to Neurosurgical Implications.Frontiers in neurology · 2022Review
- Cerebellar Volumes and Sensorimotor Behavior in Autism Spectrum Disorder.Frontiers in integrative neuroscience · 2022Article
- Recent Investigations on the Functional Role of Cerebellar Neural Networks in Motor Functions & Nonmotor Functions -Neurodegeneration.Current neuropharmacology · 2022Review
- Attention Deficits Influence the Development of Motor Abnormalities in High Functioning Autism.Child psychiatry and human development · 2021Article
- The human cerebellum is essential for modulating perceptual sensitivity based on temporal expectations.eLife · 2021Article
- Diminished social attention in pediatric brain tumor survivors: Using eye tracking technology during naturalistic social perception.Neuropsychology · 2020Article
- Structured reviews for data and knowledge-driven research.Database : the journal of biological databases and curation · 2020Article
- Frequency-Tagging Electroencephalography of Superimposed Social and Non-Social Visual Stimulation Streams Reveals Reduced Saliency of Faces in Autism Spectrum Disorder.Frontiers in psychiatry · 2020Article
- Cortico-cerebellar networks for visual attention and working memory.Current opinion in psychology · 2019Review
- Distractor Inhibition in Autism Spectrum Disorder: Evidence of a Selective Impairment for Individuals with Co-occurring Motor Difficulties.Journal of autism and developmental disorders · 2019Article
- Observational Learning in Low-Functioning Children With Autism Spectrum Disorders: A Behavioral and Neuroimaging Study.Frontiers in psychology · 2018Article
- Altered Structural and Functional Connectivity of Juvenile Myoclonic Epilepsy: An fMRI Study.Neural plasticity · 2018Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Recent imaging and clinical studies have challenged the concept that the functional role of the cerebellum is exclusively in the motor domain. We present evidence of slowed covert orienting of visuospatial attention in patients with developmental cerebellar abnormality (patients with autism, a disorder in which at least 90% of all postmortem cases reported to date have Purkinje neuron loss), and in patients with cerebellar damage acquired from tumor or stroke. In spatial cuing tasks, normal control subjects across a wide age range were able to orient attention within 100 msec of an attention-directing cue. Patients with cerebellar damage showed little evidence of having oriented attention after 100 msec but did show the effects of attention orienting after 800-1200 msec. These effects were demonstrated in a task in which results were independent of the motor response. In this task, smaller cerebellar vermal lobules VI-VII (from magnetic resonance imaging) were associated with greater attention-orienting deficits. Although eye movements may also be disrupted in patients with cerebellar damage, abnormal gaze shifting cannot explain the timing and nature of the attention-orienting deficits reported here. These data may be consistent with evidence from animal models that suggest damage to the cerebellum disrupts both the spatial encoding of a location for an attentional shift and the subsequent gaze shift. These data are also consistent with a model of cerebellar function in which the cerebellum supports a broad spectrum of brain systems involved in both nonmotor and motor function.
Indexed as
Identifiers
10377369PMC6782343What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.