Evidence map›Paper›PMID 10375387›Full record

ReviewJournal of thrombosis and thrombolysis1999

Heparin induced thrombocytopenia: diagnosis and contemporary antithrombin management.

J L Januzzi, I K Jang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of thrombosis and thrombolysis, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 23 citations in OpenAlex.

  1. Argatroban.Journal of thrombosis and thrombolysis · 2002
    Review
  2. Review
  3. Drug-induced thrombocytopenia in the coronary care unit.Journal of thrombosis and thrombolysis · 2000
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

J L JanuzziCardiology Division, Massachusetts General Hospital, Harvard Medical School Boston, Massachusetts 02114, USA.
I K Jang
Massachusetts General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heparin-induced thrombocytopenia (HIT) may be complicated by severe thrombotic complications and death. Currently no specific laboratory test is available to make the diagnosis. When HIT is clinically suspected, heparin should be discontinued immediately. While no specific therapy for HIT exists, there is increasing evidence that acute antithrombin therapy may significantly reduce morbidity and mortality. Among several agents, the direct antithrombins, such as r-hirudin and argatroban, look the most promising for acute treatment.

Indexed as

AncrodArginineChondroitin SulfatesDermatan SulfateDrug CombinationsFibrinolytic AgentsForecastingGangreneHemorrhageHeparan SulfateHeparinHirudinsHirudin TherapyHumansPipecolic AcidsPlatelet AggregationAncrodargatrobanArginineChondroitin SulfatesdanaparoidDermatan SulfateDrug CombinationsFibrinolytic AgentsHeparan SulfateHeparinHirudinslepirudinPipecolic AcidsProtein CRecombinant ProteinsSulfonamidesThrombinWarfarin

Identifiers

PMID10375387
OpenAlexW1938034767

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.