Evidence map›Paper›PMID 10372967›Full record

ArticleGlycoconjugate journal1998

In-situ hybridization localized MUC7 mucin gene expression to the mucous acinar cells of human and MUC7-transgenic mouse salivary glands.

S H Khan, A Aguirre, L A Bobek

Abstract read
PubMed Publisher
In one paragraph

Article in Glycoconjugate journal, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. The gastrointestinal mucus system in health and disease.Nature reviews. Gastroenterology & hepatology · 2013
    Review
  5. An unusual glycoform of human salivary mucin MG2.Clinical oral investigations · 2012
    Article
  6. Article
  7. Functional analysis of human MUC7 mucin gene 5'-flanking region in lung epithelial cells.American journal of respiratory cell and molecular biology · 2006
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

S H KhanDepartment of Oral Biology, School of Dental Medicine, State University of New York, Buffalo, USA.
A Aguirre
L A Bobek
University at Buffalo, State University of New York · US

Funding

STRUCTURE/REGULATION OF HUMAN SALIVARY APO MUCIN GENESP01DE007585 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI LAU, JOSEPH T.Y. · 1988 to 1998
–
TITANIUM ALLOYS FOR PARTIAL DENTURESR43DE007034 · NIDCR · GREENMARK, INC. · PI MARKER, BERNARD C · 1985 to 1985
–
NIDCR NIH HHS DE 07034NIDCR NIH HHS DE 07585
6 · The paper itself

Abstract

MUC7 gene that encodes the low molecular weight human salivary mucin MG2, was previously shown to be expressed in tissue-specific manner in normal human salivary glands and in salivary glands of transgenic mice carrying the MUC7 transgene. The purpose of this study was to examine the cell specificity of MUC7 expression in human and transgenic mice salivary glands. To localize the MUC7 transcripts, we used in-situ hybridization in combination with Tyramide Signal Amplification procedure. The results clearly showed that in both the human and transgenic mice salivary gland tissue sections, MUC7 transcripts were localized only in mucous acinar cells; no signals were found in serous acinar cells or any other cell types present in these salivary glands.

Indexed as

AnimalsFemaleHumansIn Situ HybridizationMaleMiceMice, TransgenicMucinsRNA, MessengerSalivary GlandsSalivary Proteins and PeptidesMUC7 protein, humanMucinsRNA, MessengerSalivary Proteins and Peptides

Identifiers

PMID10372967
OpenAlexW72939679

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.