ArticleThe Plant cell1999
Matrix attachment region binding protein MFP1 is localized in discrete domains at the nuclear envelope.
Article in The Plant cell, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 69 citations in OpenAlex.
- Dual targeting and retrograde translocation: regulators of plant nuclear gene expression can be sequestered by plastids.International journal of molecular sciences · 2012Review
- The senescence-induced staygreen protein regulates chlorophyll degradation.The Plant cell · 2007Article
- Dual location of MAR-binding, filament-like protein 1 in Arabidopsis, tobacco, and tomato.Planta · 2006Article
- Functional isolation of novel nuclear proteins showing a variety of subnuclear localizations.The Plant cell · 2005Article
- Economy, speed and size matter: evolutionary forces driving nuclear genome miniaturization and expansion.Annals of botany · 2005Review
- Identification of a novel plant MAR DNA binding protein localized on chromosomal surfaces.Plant molecular biology · 2004Article
- Nucleo-cytoplasmic partitioning of proteins in plants: implications for the regulation of environmental and developmental signalling.Current genetics · 2003Review
- MFP1 is a thylakoid-associated, nucleoid-binding protein with a coiled-coil structure.Nucleic acids research · 2003Article
- Four signature motifs define the first class of structurally related large coiled-coil proteins in plants.BMC genomics · 2002Article
- A new dynamin-like protein, ADL6, is involved in trafficking from the trans-Golgi network to the central vacuole in Arabidopsis.The Plant cell · 2001Article
- AHM1, a novel type of nuclear matrix-localized, MAR binding protein with a single AT hook and a J domain-homologous region.The Plant cell · 2000Article
- Conservation of matrix attachment region-binding filament-like protein 1 among higher plants.Plant physiology · 2000Article
- MAF1, a novel plant protein interacting with matrix attachment region binding protein MFP1, is located at the nuclear envelope.The Plant cell · 1999Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, it has been suggested that nuclear processes, such as replication, transcription, and splicing, are spatially organized and associated with a nuclear framework called the nuclear matrix, a structure of unknown molecular composition. It has been shown that chromatin is attached to the nuclear matrix via specific DNA fragments called matrix attachment regions (MARs). We have begun to dissect the plant nuclear matrix by isolating a DNA binding protein with specific affinity for MARs. Here, it is shown that MAR binding filament-like protein 1 (MFP1) is associated with specklelike structures at the nuclear periphery that are part of isolated nuclei and the nuclear matrix. A predicted N-terminal transmembrane domain is necessary for the specific targeting of MFP1 to the speckles, indicating an association with the nuclear envelope-endoplasmic reticulum continuum. In addition, it is shown that a marker protein for plant microtubule organizing centers, which has been shown to be localized on the outside of the plant nuclear envelope, is also part of the nuclear matrix. These findings indicate a close and previously undescribed connection in plants between the nuclear envelope and the internal nuclear matrix, and they suggest a function for MFP1 in attaching chromatin to specific sites at the nuclear periphery.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.