ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience1999
Cell-surface glycoprotein of oligodendrocyte progenitors involved in migration.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
26 citing papers in PubMed, 83 citations in OpenAlex.
- Neuroligin-3-CSPG4 interaction maintains oligodendrocyte precursor cell progenitor state and promotes glioma proliferation through mechanotransduction.Nature neuroscience · 2026Article
- Transcriptional dynamics of the oligodendrocyte lineage and its regulation by the brain erythropoietin system.Nature communications · 2025Article
- Early life adversity targets the transcriptional signature of hippocampal NG2+ glia and affects voltage gated sodium (NaNeurobiology of stress · 2021Article
- Acute brain injuries trigger microglia as an additional source of the proteoglycan NG2.Acta neuropathologica communications · 2020Article
- Article
- The Intracellular Cleavage Product of the NG2 Proteoglycan Modulates Translation and Cell-Cycle Kinetics via Effects on mTORC1/FMRP Signaling.Frontiers in cellular neuroscience · 2018Article
- Modeling neurological diseases using iPSC-derived neural cells : iPSC modeling of neurological diseases.Cell and tissue research · 2018Review
- A new in vitro mouse oligodendrocyte precursor cell migration assay reveals a role for integrin-linked kinase in cell motility.BMC neuroscience · 2016Article
- Stonin1 mediates endocytosis of the proteoglycan NG2 and regulates focal adhesion dynamics and cell motility.Nature communications · 2015Article
- The NG2 Proteoglycan Protects Oligodendrocyte Precursor Cells against Oxidative Stress via Interaction with OMI/HtrA2.PloS one · 2015Article
- Article
- Transduction of extracellular cues into cell polarity: the role of the transmembrane proteoglycan NG2.Molecular neurobiology · 2014Review
- Inhibitors of myelination: ECM changes, CSPGs and PTPs.Experimental neurology · 2014Article
- NG2 regulates directional migration of oligodendrocyte precursor cells via Rho GTPases and polarity complex proteins.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Extracellular acidic pH inhibits oligodendrocyte precursor viability, migration, and differentiation.PloS one · 2013Article
- NG2 cells: Properties, progeny and origin.Brain research reviews · 2010Review
- Oligodendrocytes: biology and pathology.Acta neuropathologica · 2010Review
- Identification of Tmem10/Opalin as a novel marker for oligodendrocytes using gene expression profiling.BMC neuroscience · 2008Article
- Analysis of axonal regeneration in the central and peripheral nervous systems of the NG2-deficient mouse.BMC neuroscience · 2007Article
- Origin of oligodendrocytes in the subventricular zone of the adult brain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Myelination by oligodendrocytes in the CNS involves the migration to and recognition and ensheathment of axons. These distinct developmental phases of myelination are assumed to involve the interplay of a precisely regulated set of cell adhesion molecules expressed by both neurons and glial cells. These molecules remain largely unelucidated. In this paper we have identified a large (330 kDa) glycoprotein expressed by murine oligodendrocyte progenitor cells in vitro and in vivo that is downregulated as oligodendrocytes mature. Antigen-positive oligodendrocyte progenitor cells purified by panning develop into myelin-associated glycoprotein-positive oligodendrocytes and also adhere to cultured neurons. Polyclonal antibodies directed against the protein reduce the migration of oligodendrocyte progenitor cells. The observations suggest that the AN2 antigen may play a role in early stages of myelination.
Indexed as
Identifiers
10366628PMC6782645W1490096362What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.