ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience1999
Olfactory adaptation depends on the Trp Ca2+ channel in Drosophila.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed.
- Article
- Article
- Article
- Review
- Olfaction in patients with Parkinson's disease: a new threshold test analysis through turning points trajectories.Journal of neural transmission (Vienna, Austria : 1996) · 2021Article
- Brief Report: Olfactory Adaptation in Children with Autism Spectrum Disorders.Journal of autism and developmental disorders · 2019Article
- Prior contact with permethrin decreases its irritancy at the following exposure among a pyrethroid-resistant malaria vector Anopheles gambiae.Scientific reports · 2019Article
- Effect of DEET-multiple exposures on behavior and life history traits in the malaria mosquito Anopheles gambiae (s.s.).Parasites & vectors · 2018Article
- Colony-level non-associative plasticity of alarm responses in the stingless honey bee, Tetragonisca angustula.Behavioral ecology and sociobiology · 2018Article
- The Two Main Olfactory Receptor Families inFrontiers in cellular neuroscience · 2018Review
- Article
- Insect odorant receptor trafficking requires calmodulin.BMC biology · 2016Article
- Distinct signaling of Drosophila chemoreceptors in olfactory sensory neurons.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Modification of Male Courtship Motivation by Olfactory Habituation via the GABAA Receptor in Drosophila melanogaster.PloS one · 2015Article
- Repellence produced by monoterpenes on Rhodnius prolixus (Hemiptera: Reduviidae) decreases after continuous exposure to these compounds.Journal of insect science (Online) · 2014Article
- Evolutionarily conserved, multitasking TRP channels: lessons from worms and flies.Handbook of experimental pharmacology · 2014Article
- Article
- Early olfactory processing in Drosophila: mechanisms and principles.Annual review of neuroscience · 2013Review
- Transcriptional basis of the acclimation to high environmental temperature at the olfactory receptor organs of Drosophila melanogaster.BMC genomics · 2013Article
- Aedes aegypti mosquitoes exhibit decreased repellency by DEET following previous exposure.PloS one · 2013Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Olfactory adaptation is shown to occur in Drosophila, at both behavioral and physiological levels. In a behavioral paradigm, the extent of adaptation is shown to depend on the dose and duration of the adapting stimulus. Half-maximal adaptation occurred after 15 sec of exposure to an odor, and recovery occurred with a half-time of 1. 5 min, under a set of test conditions. Cross-adaptation was observed among all odor combinations tested, although to a lesser extent than when the same odor was used as both the adapting and the test stimulus. Mutants of the transient receptor potential (Trp) Ca2+ channel were normal in olfactory response, but defective in olfactory adaptation, when measured either behaviorally or in tests of antennal physiology. These results indicate that olfactory response and adaptation can be distinguished. Trp expression was detected in the developing antenna but, surprisingly, not in the mature antenna. These results, together with temperature-shift analysis of a temperature-sensitive trp mutant, provide evidence of a role of Trp in olfactory system development.
Indexed as
Identifiers
10366618PMC6782652What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.