ArticleInternational journal of experimental pathology1999
Degradation of Japanese encephalitis virus by neutrophils.
Article in International journal of experimental pathology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 50 citations in OpenAlex.
- Spatial transcriptomics uncovers vasculature-centered cellular interactions driving Japanese encephalitis progression in a mouse model.Nature communications · 2026Article
- Japanese Encephalitis Virus-Infected Cells.Sub-cellular biochemistry · 2023Article
- Neutrophil Recruitment and Participation in Severe Diseases Caused by Flavivirus Infection.Life (Basel, Switzerland) · 2021Review
- Adults with severe Japanese encephalitis: a retrospective analysis of 9 cases in Linyi, China.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Article
- Article
- Pancreas of coxsackievirus-infected dams and their challenged pups: A complex issue.Virulence · 2019Article
- Review
- The intrathecal expression and pathogenetic role of Th17 cytokines and CXCR2-binding chemokines in tick-borne encephalitis.Journal of neuroinflammation · 2018Article
- CD14Nature microbiology · 2017Article
- Japanese Encephalitis Virus Infection Results in Transient Dysfunction of Memory Learning and Cholinesterase Inhibition.Molecular neurobiology · 2017Article
- Temporal changes of Japanese encephalitits virus in different brain regions of rat.The Indian journal of medical research · 2013Article
- Status of proinflammatory and anti-inflammatory cytokines in different brain regions of a rat model of Japanese encephalitis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2012Article
- Alteration in plasma glucose levels in Japanese encephalitis patients.International journal of experimental pathology · 2002Article
- Antiviral effect of nitric oxide during Japanese encephalitis virus infection.International journal of experimental pathology · 2000Article
- An enzyme immunoassay for detection of Japanese encephalitis virus-induced chemotactic cytokine.Journal of biosciences · 2000Article
- Evaluation of antiviral activity of essential oil of Trachyspermum Ammi against Japanese encephalitis virus.Pharmacognosy researchArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ability of neutrophils to degrade the phagocytosed Japanese encephalitis (JE) virion, via triggering of the respiratory burst and generation of toxic radicals has been investigated. JEV or JEV-induced macrophage derived factor (MDF) induces increase in intracellular oxidative signals with generation of superoxide anion (O2-), via activation of cytosolic NADPH and subsequent formation of hydrogen peroxide, with maximum activity on day 7 post infection. The response was sensitive to anti-MDF antibody treatment. Further, the study revealed rapid degradation of phagocytosed JE viral protein and nucleic acid. The viral protein degradation was partially dependent on the generation of toxic oxygen species as it could be abrogated by pretreatment of the cells with staurosporine.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.