ArticleJournal of clinical microbiology1999
Detection of Helicobacter pylori DNA in fecal samples from infected individuals.
Article in Journal of clinical microbiology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- Non-invasive diagnostic tests for Helicobacter pylori infection.The Cochrane database of systematic reviews · 2018Pooled it
- Prevalence and correlation with clinical diseases of Helicobacter pylori cagA and vacA genotype among gastric patients from Northeast China.BioMed research international · 2014Trial
- Identification, Genome Sequencing, and Characterizations ofMicroorganisms · 2023Article
- Importance of antimicrobial susceptibility testing for the management of eradication inWorld journal of gastroenterology · 2017Review
- Noninvasive molecular analysis ofWorld journal of gastroenterology · 2017Review
- Application of stool-PCR for the diagnosis of Helicobacter pylori from stool in Nigeria- a pilot study.SpringerPlus · 2012Article
- Ticks and tick-borne pathogens in livestock from nomadic herds in the Somali Region, Ethiopia.Experimental & applied acarology · 2012Article
- Five methods for detection of Helicobacter pylori in the Turkish population.World journal of gastroenterology · 2011Article
- Anaemia among clinically well under-fives attending a community health centre in Venda, Limpopo Province.South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde · 2010Article
- Helicobacter pylori detection and antimicrobial susceptibility testing.Clinical microbiology reviews · 2007Review
- Clinical role and importance of fluorescence in situ hybridization method in diagnosis of H pylori infection and determination of clarithromycin resistance in H pylori eradication therapy.World journal of gastroenterology · 2007Review
- Novel real-time PCR assay for detection of Helicobacter pylori infection and simultaneous clarithromycin susceptibility testing of stool and biopsy specimens.Journal of clinical microbiology · 2004Article
- Are Helicobacter species and enterotoxigenic Bacteroides fragilis involved in inflammatory bowel disease?Digestive diseases and sciences · 2004Article
- Species of the family Helicobacteraceae detected in an Australian sea lion (Neophoca cinerea) with chronic gastritis.Journal of clinical microbiology · 2004Article
- Evaluation of protocol using gene capture and PCR for detection of Helicobacter pylori DNA in feces.Journal of clinical microbiology · 2003Article
- Comparison of diagnostic techniques for Helicobacter cetorum infection in wild Atlantic bottlenose dolphins (Tursiops truncatus).Journal of clinical microbiology · 2003Article
- Prevalence of Helicobacter pylori in Sri Lanka as determined by PCR.Journal of clinical microbiology · 2002Article
- Accurate, noninvasive detection of Helicobacter pylori DNA from stool samples: potential usefulness for monitoring treatment.Journal of clinical microbiology · 2002Article
- Evaluation of a PCR/DNA probe colorimetric membrane assay for identification of Campylobacter spp. in human stool specimens.Journal of clinical microbiology · 2001Article
- Pretreatment with urea-hydrochloric acid enhances the isolation of Helicobacter pylori from contaminated specimens.Journal of clinical microbiology · 2001Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Stool, gastric biopsy, and serum samples were collected from 22 subjects. DNA from stool was extracted, amplified, and hybridized with primers specific for the 16S rRNA gene of Helicobacter pylori. DNA from gastric biopsy specimens was analyzed similarly for comparison. Universal primers were used to confirm successful extraction of DNA from samples. Histologic, serologic, and DNA analyses were scored in a blinded fashion. Universal primer amplification verified successful DNA extraction from all stool and gastric tissue specimens. The gastric tissue DNA assay was positive for H. pylori in 11 of the 22 subjects, correlating completely with histologic and serologic results. Stool DNA was positive for H. pylori by our molecular assay in 8 of these 11 H. pylori-positive subjects. All subjects who were negative by histologic, serologic, and gastric tissue DNA analyses were also negative by stool DNA analysis. Compared to histology, serology, and gastric tissue DNA analyses, the sensitivity of our stool DNA assay was 73%, with a specificity of 100%.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.