ArticleClinical and experimental immunology1999
Decreased interferon-gamma (IFN-gamma)-producing T cells in patients with acute Kawasaki disease.
Article in Clinical and experimental immunology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Dysbiosis of the gut microbiota as a susceptibility factor for Kawasaki disease.Frontiers in immunology · 2023Article
- The Impact of Onset Age on Eosinophils in Kawasaki Disease.Biomedicines · 2022Article
- Biotransformation of 2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine (TTBP-TAZ) can contribute to high levels of 2,4,6-tribromophenol (2,4,6-TBP) in humans.Environment international · 2022Article
- Intravenous Immunoglobulin Therapy Restores the Quantity and Phenotype of Circulating Dendritic Cells and CD4Frontiers in immunology · 2022Article
- Circulating immunocompetent cell profiles during oral cyclosporin therapy for immunoglobulin-resistant Kawasaki disease.World journal of pediatrics : WJP · 2021Article
- Kawasaki Disease and Allergic Diseases.Frontiers in pediatrics · 2020Review
- Lower CMV and EBV Exposure in Children With Kawasaki Disease Suggests an Under-Challenged Immune System.Frontiers in pediatrics · 2020Article
- Article
- Pathogenetic determinants in Kawasaki disease: the haematological point of view.Journal of cellular and molecular medicine · 2017Review
- Pediatric Kawasaki Disease and Adult Human Immunodeficiency Virus Kawasaki-Like Syndrome Are Likely the Same Malady.Open forum infectious diseases · 2016Article
- Observational
- T-Helper Cytokine Profiles in Patients with Kawasaki Disease.Korean circulation journal · 2015Article
- Increased risk of atopic dermatitis in preschool children with kawasaki disease: a population-based study in taiwan.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- Article
- Polymorphisms in chemokine receptor genes and susceptibility to Kawasaki disease.Clinical and experimental immunology · 2007Article
- Anti-inflammatory effect of intravenous immunoglobulin in comparison with dexamethasone in vitro: implication for treatment of Kawasaki disease.Naunyn-Schmiedeberg's archives of pharmacology · 2006Article
- Immunological profile of peripheral blood lymphocytes and monocytes/macrophages in Kawasaki disease.Clinical and experimental immunology · 2005Review
- Family-based association analysis implicates IL-4 in susceptibility to Kawasaki disease.Genes and immunity · 2005Article
- Th1 and Th2 cytokine production is suppressed at the level of transcriptional regulation in Kawasaki disease.Clinical and experimental immunology · 2004Article
- CTLA-4 (CD152) expression in peripheral blood T cells in Kawasaki disease.Clinical and experimental immunology · 2003Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Kawasaki disease (KD) is an acute febrile illness of early childhood, in which the activation of monocytes/macrophages plays a central role in the development of vasculitis during the acute stage of disease. In this study we investigated peripheral blood T cells of 10 patients with KD, focusing on the Th1 and Th2 imbalance, using intracellular cytokine staining and analysis of the cytokine-producing T cells by flow cytometry. We observed a decrease in the numbers of IFN-gamma-producing, but not IL-4-producing, CD3+ T cells, during the acute stage. Our results suggest that there is an imbalance of Th1 and Th2 subsets during the acute stage of KD.
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