ArticleProceedings of the National Academy of Sciences of the United States of America1999
Phytoremediation of methylmercury pollution: merB expression in Arabidopsis thaliana confers resistance to organomercurials.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 272 citations in OpenAlex.
- Identification of perrhenate-binding peptides by phage display.RSC advances · 2026Article
- Improving NiInternational journal of molecular sciences · 2024Article
- Overexpression of bacterial γ-glutamylcysteine synthetase increases toxic metal(loid)s tolerance and accumulation in Crambe abyssinica.Plant cell reports · 2024Article
- Phytoremediation and Microorganisms-Assisted Phytoremediation of Mercury-Contaminated Soils: Challenges and Perspectives.International journal of environmental research and public health · 2021Review
- Transgenic merA and merB expression reduces mercury contamination in vegetables and grains grown in mercury-contaminated soil.Plant cell reports · 2020Article
- Describing the toxicity and sources and the remediation technologies for mercury-contaminated soil.RSC advances · 2020Review
- The knowledge domain and emerging trends in phytoremediation: a scientometric analysis with CiteSpace.Environmental science and pollution research international · 2020Article
- Article
- Ectopic expression of a bacterial mercury transporter MerC in root epidermis for efficient mercury accumulation in shoots of Arabidopsis plants.Scientific reports · 2019Article
- Effects of growth agents and mercury on several herbs.Environmental science and pollution research international · 2018Article
- Recent advances in conventional and contemporary methods for remediation of heavy metal-contaminated soils.3 Biotech · 2018Review
- Phytoextraction of Heavy Metals: A Promising Tool for Clean-Up of Polluted Environment?Frontiers in plant science · 2018Review
- Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon-Metal Bond Cleavage.Journal of the American Chemical Society · 2017Article
- Potential Biotechnological Strategies for the Cleanup of Heavy Metals and Metalloids.Frontiers in plant science · 2016Review
- In situ remediation technologies for mercury-contaminated soil.Environmental science and pollution research international · 2015Review
- Antioxidant responses in the leaves of mercury-treated Eichhornia crassipes (Mart.) Solms.Environmental monitoring and assessment · 2014Article
- Pollution due to hazardous glass waste.Environmental science and pollution research international · 2014Review
- Article
- Metallothionein expression in chloroplasts enhances mercury accumulation and phytoremediation capability.Plant biotechnology journal · 2011Article
- Perspectives for genetic engineering of poplars for enhanced phytoremediation abilities.Ecotoxicology (London, England) · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Methylmercury is an environmental toxicant that biomagnifies and causes severe neurological degeneration in animals. It is produced by bacteria in soils and sediments that have been contaminated with mercury. To explore the potential of plants to extract and detoxify this chemical, we engineered a model plant, Arabidopsis thaliana, to express a modified bacterial gene, merBpe, encoding organomercurial lyase (MerB) under control of a plant promoter. MerB catalyzes the protonolysis of the carbon---mercury bond, removing the organic ligand and releasing Hg(II), a less mobile mercury species. Transgenic plants expressing merBpe grew vigorously on a wide range of concentrations of monomethylmercuric chloride and phenylmercuric acetate. Plants lacking the merBpe gene were severely inhibited or died at the same organomercurial concentrations. Six independently isolated transgenic lines produced merBpe mRNA and MerB protein at levels that varied over a 10- to 15-fold range, and even the lowest levels of merBpe expression conferred resistance to organomercurials. Our work suggests that native macrophytes (e.g., trees, shrubs, grasses) engineered to express merBpe may be used to degrade methylmercury at polluted sites and sequester Hg(II) for later removal.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.