Evidence map›Paper›PMID 10359642›Full record

ArticleThe Biochemical journal1999

Molecular cloning and immunolocalization of a novel vertebrate trp homologue from Xenopus.

L K Bobanovic, M Laine, C C Petersen, D L Bennett, M J Berridge, P Lipp, S J Ripley, M D Bootman

Open access · greenAbstract read
In one paragraph

Article in The Biochemical journal, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Ion Channel Function During Oocyte Maturation and Fertilization.Frontiers in cell and developmental biology · 2018
    Review
  3. Article
  4. Postsynaptic TRPC1 function contributes to BDNF-induced synaptic potentiation at the developing neuromuscular junction.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011
    Article
  5. Asymmetric PI(3,4,5)P3 and Akt signaling mediates chemotaxis of axonal growth cones.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011
    Article
  6. Sonic hedgehog signaling is decoded by calcium spike activity in the developing spinal cord.Proceedings of the National Academy of Sciences of the United States of America · 2011
    Article
  7. Stretch-activated cation channel from larval bullfrog skin.The Journal of experimental biology · 2010
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

L K BobanovicLaboratory of Molecular Signalling, The Babraham Institute, Babraham, Cambridge CB2 4AT, UK.
M Laine
C C Petersen
D L Bennett
M J Berridge
P Lipp
S J Ripley
M D Bootman
University of Cambridge · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

We report the sequence, structure and distribution of a novel transient receptor potential (trp) homologue from Xenopus, Xtrp, determined by screening an oocyte cDNA library. On the basis of sequence similarity and predicted structure, Xtrp appears to be a homologue of mammalian trp1 proteins. Two polyclonal antibodies raised against distinct regions of the Xtrp sequence revealed Xtrp expression in various Xenopus tissues, and the localization of Xtrp at the plasma membrane of Xenopus oocytes and HeLa cells. Since capacitative calcium entry into Xenopus oocytes has been shown previously to be substantially inhibited by trp1 antisense oligonucleotides [Tomita, Kaneko, Funayama, Kondo, Satoh and Akaike (1998) Neurosci. Lett. 248, 195-198] we suggest that Xtrp may underlie capacitative calcium entry in Xenopus tissues.

Indexed as

Drosophila ProteinsAmino Acid SequenceAnimalsAntibodiesBase SequenceCalmodulin-Binding ProteinsCell MembraneCloning, MolecularGene LibraryHeLa CellsHumansImmunohistochemistryMembrane ProteinsMolecular Sequence DataMolecular WeightOocytesAntibodiesCalmodulin-Binding ProteinsDrosophila ProteinsMembrane ProteinsTransient Receptor Potential Channelstrpl protein, Drosophila

Identifiers

PMID10359642
PMCPMC1220289
OpenAlexW2019562200

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.