ArticleJapanese journal of cancer research : Gann1999
Comparative case-referent study of risk factors among hormone-related female cancers in Japan.
Article in Japanese journal of cancer research : Gann, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 5 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 5 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Age at Menopause and Risk of Developing Endometrial Cancer: A Meta-Analysis.BioMed research international · 2019Pooled it
- Breastfeeding and maternal health outcomes: a systematic review and meta-analysis.Acta paediatrica (Oslo, Norway : 1992) · 2015Pooled it
- Pooled it
- Association between Breastfeeding and Endometrial Cancer Risk: Evidence from a Systematic Review and Meta-Analysis.Nutrients · 2015Pooled it
- Breastfeeding and ovarian cancer risk: a meta-analysis of epidemiologic studies.The American journal of clinical nutrition · 2013Pooled it
- Reduced risk of endometrial cancer from alcohol drinking in Japanese.Cancer science · 2008Trial
- Association between body mass index and incidence of breast cancer in premenopausal women: a Japanese nationwide database study.Breast cancer research and treatment · 2022Article
- Association of Mammary Gland Disease With Metabolic Syndrome Factors in Japanese Women-Case-Control Study Based on Health Screening Results.Breast cancer : basic and clinical research · 2022Article
- Association Between Breastfeeding and Ovarian Cancer Risk.JAMA oncology · 2020Article
- Predictors of pretreatment CA125 at ovarian cancer diagnosis: a pooled analysis in the Ovarian Cancer Association Consortium.Cancer causes & control : CCC · 2017Article
- Weight gain during adulthood and body weight at age 20 are associated with the risk of endometrial cancer in Japanese women.Journal of epidemiology · 2011Article
- Association between dietary calcium and vitamin D intake and cervical carcinogenesis among Japanese women.European journal of clinical nutrition · 2010Article
- DNA repair gene ERCC2 polymorphisms and associations with breast and ovarian cancer risk.Molecular cancer · 2008Article
- Evidence in favour of lifestyle intervention for cancer prevention with special reference to colorectal cancer.Environmental health and preventive medicine · 2004Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To assess the impact of reproductive and anthropometric factors as a risk indicator for female cancers in hormone-related organs, i.e., the breast, endometrium and ovary, we conducted a comparative case-referent study using data from the Hospital-based Epidemiologic Research Program at Aichi Cancer Center (HERPACC), Japan. The case group consisted of 1,465, 133 and 99 women who had first been diagnosed as having breast, endometrial and ovarian cancer, respectively. The referents were 25,488 female first-visit outpatients who had not previously been diagnosed with any type of cancer. The odds ratios (ORs) and their 95% confidence intervals (95%CI) were estimated using an unconditional logistic regression model. An inverse association with experience of delivery and a positive association with body mass index (BMI) and with change of BMI after 20 years of age, were observed consistently for all three cancer sites. We observed similar risk and protective factors for breast and endometrial cancer, but the effect of reproduction and overweight condition (BMI> or =25) were more prominent in endometrial cancer. Although the present study failed to find site-specific risk factors for ovarian cancer, the results provided evidence that being overweight and/or weight gain in adult life is a common risk factor for all three cancer sites. The results obtained from this study suggested that avoidance of weight gain may reduce the risk of female hormone-related cancers.
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